thread: Long Term TTC & Assisted Conception Oct #2 2012

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  1. #11

    Jun 2010
    District Twelve
    8,425

    Hiya Bloss!

    The ppet is an injection of HCG into the uterus at the time of transfer.

    I copied the following about filgrastim .....


    Neupogen (filgrastim) is a drug that causes the body to generate neutrophils, a type of white blood cell which plays an important role in the immune system. Our clinic has investigated its use in fertility treatment as a solution to certain immunologic causes of multiple miscarriages. It has often proven successful when other options have failed. You may benefit from using Neupogen if you have experienced recurrent miscarriages after failed IVIG or LIT and if you meet specific criteria for treatment. The drug is also useful in many cases for the purpose of improving egg quality or improving the tissues of the uterine lining. Our clinic has the largest number of patients in the country that have been treated with Neupogen for failure to initiate and complete a pregnancy. It is critical that your treating physician has vast experience with the use of this drug for fertility.

    G-CSF(neupogen) is a cell-signaling protein molecule that can assist with maintaining the immune system in a "resting" state so it will not attack the embryo, it may increases the number of good quality eggs during an in vitro fertilization (IVF) cycle, increase the number of uterine natural killer cells(which assist in embryo attachment), increase embryo cell division, endometrial cell division and may even reduce inlammatory cytokine production... Patients with recurrent pregnancy loss that have been treated with G-CSF have shown higher pregnancy rates with no evidence to date of complications to mother or baby. You may be a candidate if you've experienced:

    Recurrent miscarriages that have failed IVIG, LIT and meet immunologic criteria for treatment; or
    Repeat failed IVF cycles with quality embryos (must also meet certain immunologic criteria)
    Last edited by nothing2lose; November 4th, 2012 at 08:10 PM.