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Bec, I am so terribly sorry for your loss. I wish things were differently. Just know that we are all here for you, whatever you decide.
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Hi Ladies
Well my spotting dissapeared yesterday so FX it stays away.
I've been temping again and my temps are pretty low. FF has put me down to O between the 1st & 7th May so that would mean AF should be due around the 16th May. Not sure if that will happen because of the M/C and also my PCOS.
So I thought i'd start doing my OPK's tonight and see if we get a + any time soon.
Well we'll see what happens.
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Thanks guys.
Porsche- GL with o. Catch the egg, love! Glad the spotting has stopped.
Julia- Thanks hon. I have started bleeding now, so at least I won't have to take anything to get that happening.
Hi everyone else! Many of you must just about be TWWing by now. How's it going?
AFM: We had only told our parents and my sisters about the pregnancy, and last night I had to let them all know there wasn't one any more. My mother in law and step mum were devastated, which set me off again. If I get pregnant again I wont tell them untill 12 weeks, it's not fair to put them through that again.
I have thrown myself into researching what went wrong. I didn't know that the m/c rate in women with PCOS is possibly as high as 45%! How did the dr not tell me that? I have found that women who take metformin have a much lower chance of m/c (normal level), so I'm going to ask my specialist about that. It can take a few months to reduce the insulin levels and problems with ovaries, but I couldn't try again straight away anyway. Who else is on metformin? Is it terrible expensive? I'm not taking clomid again untill I get this resolved becasue obviously there is some underlying thing going on.
I'm so sorry for the long rant all about ME. I just had to get it off my chest.
Bec
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Hello Everyone
Just thought I would give a quick update. I had my CD12 scan (on cd11) yesterday and my right ovary has produced approximately 6 follicles. 4 of those are top notch good to go. I had my 10000 i.u. Pregnyl injection yesterday and was told to BD 36 hours after that. Has anyone else here had the same sort of treatment? My doc wasnt too clear on all the details for conception.majorly.
Saffy - Thanks for thinking of me yesterday. That was real nice of you.
RhiChiChi - Thankyou. I really hope the higher dosage brings more luck also.
Trying To - Sorry to hear of your m/c. This is only my second cycle of Clomid but I tend to get alot of hot flushes and bad lower back pain. The pain heightens at ovulation. Hang in there, FX for you that something will happen soon. I know one of the symptoms of clomid is bloating.
Bec - I am so terribly sorry to hear about your loss. It makes me sad to hear what you are currently going through. Don't apologise for your "rant", it helps to let it all out. Only you will know when your ready to move to the next step. Thinking and praying for you also.
Quick question: what is AFM? Sorry, still working out the lingo.
Hello to everyone else and wishing you all the best of luck.
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Hi Bec
I was very interested in your research about PCOS & M/C. Does that include a blighted ovum? It seemed in my case that everything was doing fine but the baby didn't develop. Something about too many chromazomes or something? I think I might ask the FS on Tuesday when I call.
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hi bec
i have been on metformin for about 18 months - 2 years. When i first got preg i stopped taking it because i was unsure if i should take it or not (didnt see the dr for 2 weeks) in the time i had stopped i did m/c, dont know if it was caused by the not taking metformin or because when i found out i was in emergency and had x-rays and scans and morphine. But i do think taking it in the first place had everything to do with me getting preg.
As for cos it is about $10 or less $5 concession for the less expensive brand (diaformin) and you get about 50 tabs i think.
The only prob i have with it is if i dont take it with food i i get an upset tummy and end up on the toilet lots.
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Bec- I'm so so sorry, you bought a tear to my eye when I read about telling your family, it must have been difficult
I don't know anything much about PCOS, but I hope your Dr does all the investigations necessary and you get an answer soon x
Porsche- I had a blighted ovum too, I don't think its related to PCOS, its just a chromosomal problem in the egg which is more common the older you get and its unusual to have it happen more than once. Glad spotting has stopped for you. I took your advice and I got some EWCM yesterday!
Hope- sounds like a good result, hope you are getting jiggy with it soon! AFM is "as for me" when you want to talk about yourself!
Rhichichi- hope all is well with you today x
Hi to Tamarra, Tryingto and Linda-
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I just wanted to sneak in and say how sorry I am to hear of your loss Bec.
Sending you lots and lots of
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Hello Tammara
you probably already know this but I was just googling and found this:
"Do I stop Metformin if I'm pregnant?
No. Several studies have shown that if metformin helps you get pregnant then taking it for the first 3 months also helps to reduce the risk of a miscarriage.
Metformin should be stopped before the second half of pregnancy because it can lower glucose levels in the baby, and this is not a good thing leading up to birth."
Hope this helps a bit.
Sorry to hear about your loss. FX for next time.
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Bec - As per Hope's post above, I have heard it is best to stay on Metformin whilst pg & gradually wean yourself off it during pg - a cyber friend of mine did that & she has a healthy little girl after many, many years of ttc. Her daughter is only a few months old but I know one of her sons just turned 18, so that gives you an idea of how long she had been ttc for. She swears that when she fell pg & stopped Metformin that it was the cause of one of her m/c......
I'm sorry your sad news affected your family so badly- one of my greatest fears is sharing that we are pg then having to tell them of another m/c.... We never told anyone we were pg the first two times (both were 5/6 weeks losses) then after that I told my mum b/c I needed support. Most people we don't tell til 12 weeks.
Hope - AFM = as for me. Sorry can't help you with your question.
Hellp to everyone else, got to go
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Hi girls,
Porsche- I got on a website called POSAA which is the polycystic ovary syndrom association of australia and it had quite a bit of interesting research that I didn't know. I alos typed in "reducing risk of miscarriage in women with PCOS" and a great article about a study that had been done came up too. Apparently they don't really know why PCOS caused miscarriage, there are a gamet of reasons becasue there are a gamet of reasons women get the syndrome, so I'm not sure about blighted ovum or chromosonal stuff. I'll have a look though. It was interesting and I want to know why my doc didn't give me any info when I was diagnosed!
Hope- I had the same treatment as you with the follies check and then pregnal. Apparently you o about 24-48 hours after the injection. DTD every night untill you o and then the night after also, my dr said. HTH.
Julia- I was so excited when we found out and both our families have been following our progress. We have a good relationship with both of our families, and they were as excited as we were. I should have thought about how it would affect them, but I was selfishly excited and wanted to share with someone. I know for next time. Interestingly the article I read on metformin and PCOS said that if a woman has a had a miscarriage before she should continue to take metformin in the first trimester to reduce m/c. It was very interesting. Thanks for the info though.
Tammara- thanks for the info on metformin. did your FS prescribe that? My FS has never even mentioned it. I didn't know you had lost one before. It makes your miracle now all the more so doesn't it?
Hi Elocin and Saffy- thanks for your support. And SAffy, I got lots of tests done last time I m/c so not sure what he'll do this time. But I plan to be quite persistent!
Hi Keli- Thanks love. Glad everything is still well with you
Thanks so much for listening (well figuratively IYKWIM!). It is great having some poeple to talk to who know what it's all like. It makes me feel much less alone.
Have a good weekend,
Bec
Last edited by onthefly; April 30th, 2010 at 05:36 PM. : Removing commercial link.
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This was from that article:
Compared to clomiphene citrate in normal-weight women with PCOS, metformin had a similar ovulation rate (63 vs 67%) but superior pregnancy rates (69 vs 34%) and miscarriage rates (10 vs 38%)6. As metformin was ceased at diagnosis of pregnancy, it would appear that the reduction in prevalence of miscarriage results when metformin is taken prior to rather than after conception. In a carefully controlled trial over 6 months comparing laparoscopic ovarian diathermy (“golf-balling”) with metformin in PCOS women who had not responded to clomiphene, metformin had an identical ovulation rate (55%) but superior pregnancy rates (19 vs 13%) and miscarriage rates (15 vs 29%)7.
Metformin, with exercise and diet, will restore fertility in most women whose PCOS is due to insulin resistance, reducing the need for more costly, invasive and emotionally stressful assisted reproductive interventions.
In two studies, metformin taken before and during pregnancy dramatically reduced the high miscarriage rate seen in PCOS from 42% to 9%8,9. Metformin has now been used extensively during pregnancy for four years without apparent ill-effects but with reduced rates of gestational diabetes10 and severe hypertension in the 3rd trimester. Metformin occasionally reduces absorption of vitamin B12 and B12 levels should be checked in pregnancy.
Here's the link to the whole article:http://www.posaa.asn.au/files/PCOS%20Guide.pdf
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Hi ladies,
please don't take this the wrong way as I most certainly don't want to come in here & glote, but I do know that good news helped my very long ttc journey, so I hope you are all ok with me saying this!
Just wanted to let you all know that we had our 6 & 1/2 week scan today, only one bub and everything is great, heartbeat is at 124bpm and bub is now 4mm long! I am so very relieved as I was very concerned that something was going to be wrong!
Thank you to all you wonderful ladies, you have all been amazing through my journey. I will always keep an eye on you all and pop in to say hi from time to time! I can honestly never thank you all enough!
A special hug to Porsche & Bec, I can only imaging what you are both going through! I only hope that your recovery is quick & your journey is short! Love to you both Xxoo
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Hi Ladies,
I actually tried to post this yesterday but I lost it. So if a message similar to this is floating around out there, sorry.
So anyway, I wanted to update you on how I am going with Femara. Now, when I say all this please keep in mind that this is my first run on fertility drugs so I don't have anything to compare to like clomid.
But let me tell you, I HATE IT!!! I started the drugs on Monday, taking them at night time. I have had hot flushes and head aches every day since. Tonight is my last pill so I am hoping that after Saturday these symptoms will pass.
I guess the test will be on Tuesday when I go for a scan to see if I have made any progress.
Good luck everyone and I hope your journey is quick.
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Hey everyone
Hope - i definately think my m/c was a combination of lots, i went into emergency with severe galblladder pain and had exrays, cat scan and some radiology scan aswell as morphene. I had no clue that i would be preg but as i was about to leave the dr came in and told us. And i stopped taking the metformin. I do believe that it was not my time to carry a baby because a few months later i was in surgery having the galbladder out.
Bec - the first thing my FS asked me was about PCOS symptoms and then he got his lil pad out and perscribed it for me to start that day, i think my first appointment was November December and i fell preg late Jan early feb. We had not been using protection for about 10 years and never got preg (unless i m/c which is possible) so i do think the metformin did something, definately would ask for it.
AFM - i had yet another scan today, i had cramps and bleeding tuesday but everything looks good. Besided the ultrasound man being ummm odd to put it nicely. I told him i just want to know there is a heart beat then he tells me oh no that doesnt mean good, he says he had a lady last week with a lovely strong heartbeat but the baby had no head or limbs! last thing i wanted to hear, then he says it good i have my "granny" with me, pitty it was my mum lol
Have a great weekend ladies xxoo
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Bec - Thanks for the info on PCOS & met. My GP told me I had PCOS but then the OBS/GYNO said I don't plus I has the test for insulin resistance and I am ok there, so Met probably is a waste of time for me.... I do have a script though cos the GP just gave it to me assuming I would be insulin resistant..... makes me want to take it....*insert naughty laugh here*
Keli - I am so relieved that all is going well for you, such great news after some not so good news. Anyway, glad you popped in & hope all continues to go well
Nelly - So sorry Femara is not giving you a good run.... I actually thought it was better than Clomid? Could be a myth then. I can sympathise, although I am on Clomid that all the side effects s*ck..
Tammara - Thanks for popping in and letting us know how you are going & so happy it is great news (albeit the comment about your mum :S)
Have an awesome weekend all. Sending you all tons of hugs, big squishy hugs. xx
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Nelly-that sounds terrible xx
Tammara-is that u/s guy a moron or what? you do not tell people horror stories like that,then insult their mother, what a freak!!
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Hi girls,
I just realised that all that info might have been taken the wrong way! I know that you may all not want to know the goary in's and out's of PCOS. Sorry if I upset anyone.
Nelly- the first round was the hardest for me too. After that first round it took all my strength to have another go, but things got better. Hang in there!
Keli & Tam- so glad your little bubs are going well! How exciting! Tammara, something must be going around with u/s people. The lady that did mine (knowing full well why I was there) made me feel stupid and like I was wasting her time. Eventually I burst into tears and she was a bit kinder. People just don't think do they?
Julia- my insulin resistence has always been fine, but apparently sometimes your body can mask it. I'm happy to give metformin a go anyway. Then again, if they said stand on my head for three months, I would I suppose!
I'll let you know how I go at the FS tomorrow, if I don't get any answers I'm going to go to another specialist. Anyone know a good one who has any experience with PCOS?
Off to bed now, Panadeine Forte is making me sleepy (the stuff sure works though!). Night all
Bec
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