Hi Mrs P,

Sounds like you're headed in the right direction. You're right there's no point in starting fertility treatments if you're not ready to be pg yet. Jan 08 will be here before you know it!

Great that you've had all the investigations done. Very interesting that PCO has been ruled out. Causes of amenorrhoea that I've heard of are stress, low % body fat and excessive exercise. These factors affect the production of GnRH in the brain. The other hormone involved in the brain is FSH. When you have PCO the hormonal balance is out and you have lower levels of FSH and high levels of LH.

From what I understand Metformin works with your insulin levels and in some women with PCOS it is the insulin resistance that stops O. Once the insulin levels are under control cycles can normalize. From your diagnosis there's no way Metformin would help you. I'm not on Metformin. My FS has diagnosed that I have PCO but not PCOS.

Clomid can certainly cause O but I think you have to have certain natural levels of hormones for the Clomid to work. Clomid is not a hormone it merely blocks receptors in the brain and then your body does the rest. The Clomid blocks oestrogen which causes your brain to produce FSH and mature the follies. I think the Clomid has worked for me cos I have O'd naturally - just very irregularly. Perhaps your FS found that your natural levels of FSH in particular were very low and you'll need to supplement that with the injections.

HTH. Its all very confusing. As long as you're in the hands of a great FS when the time comes you'll be just fine. They know what they're doing.