Hi guys, I have an underactive thyroid, diagnosed late 2004. I have been taking thyroxine since then. I also see an endocrinologist who wants my TSH to be as close to 1 as possible. She said that if it is too low, you will have trouble conceiving and if it is too high you will more likely miscarry.

I am currently on my third IVF/ICSI cycle. My ET is tomorrow. For this cycle even though I tested negative to antipholisphoids and NK cells, we decided I would take low-dose aspirin/prednisone/clexane. So fingers crossed that it works!

Has anyone else with hypothyroidism been told to take prednisone even when they test negative for antipholisphoids etc? I think we are just trying something new for the sake of it ...

I have only been on clexane injections for four days, but man they hurt. The FSH needles are fine but the clexane needles are almost blunt. I have to use such force to get them through my stomach. And the bruises! Ouch.