I have had valve transplants in my heart and I am on warfarin permenately, except for when I am pregnant. As soon as I find out that I am pregnant, so all my pregnancies thus far have been planned I transfer over to Clexane. I have been told and have read medical journal articles explaining the benefits of Clexane during pregnancy. Primarily I switch from it as it doesn't cause deformities to the feotus or baby (unlike Warfarin does) and this is because its low molecular weight doesn't cross the placenta barrier.

I have been on Clexane for 4 pregnancies now. I have two healthy wonderful boys and I have had two miscarriages that were totally unrelated to the Clexane. The injections can sting a bit but they arn't too bad. I have been on a varied dose. For my pregnancies I started on 80mg injections twice daily and increased it to 1000mg injections twice daily as I got bigger. I need full anticoagulation and at the end of the pregnancy I switched to infractionated heparin for the induction and epidural insertion and then onto heparin infusions. All worked great.

Best of luck with your Clexane doses. It is nice to know that there are many more women out there taking Clexane (a wonder drug in my opinion... cause without it I wouldn't have my kids)

jodi
Coopydog