Very low papp-a

[frog]

I'm sorry, I have no idea about the outcomes with low Papp a, but I didn't want to read and run. My thoughts are with you both, and I'm so sorry you are having to deal with this worry

Sounds like the counselling session wasn't much help or reassurance at all, can you seek one elsewhere? You deserve to have your questions answered, and honestly. Google can have lots of helpful info, but just as much unhelpful as well...

I hope you are able to get some reassurance and more info to help with your decisions. Wishing for the best outcome for the three of you

[Charlotte91]

Google is pretty useless at times.
Same as Frog, I didn't want to read and not post.

I'm sorry you are going through this.

[~TT40~]

sorry to hear about your wife and babies results. Unfortunatly I have no personal experience but just couldn't read and not reply. Will be thinking about you and your wife in 2 days time with her CVS and really hoping for better prognosis for your baby.
I hope someone around here has some experience and can help you out.

[diannescruffy]

I'm also sorry for what you and your wife are going through. I lost my son, he had Trisomy 13 but we hadn't had any testing so didn't find out until my 20wk ultrasound. An amnio will be able to give you a diagnosis, think at around 18wks, if you have any questions feel free to ask, you will be both in my thoughts.

Regards,
Dianne

[DADDY COOL]

I'm also sorry for what you and your wife are going through. I lost my son, he had Trisomy 13 but we hadn't had any testing so didn't find out until my 20wk ultrasound. An amnio will be able to give you a diagnosis, think at around 18wks, if you have any questions feel free to ask, you will be both in my thoughts.

Regards,
Dianne

I'm sorry you lost your son Dianne. I'm guessing we are in for a similar tragedy. It isn't much fun. I hope and pray you were able to have another healthy baby.

Thanks to everybody else for the kind words

[chody47]

I am very sorry to hear you are going through this. This pregnancy we also had ver low Papp-a, but ours was a bit higher than yours at about 0.25. Our HCG was also abnormal in the sense it was 2x the average. As a result we were given a 1:59 chance of DS. We chose to have an amino at 18 weeks (which I honestly imagined would be much worse than it was) and we were given the all clear 1 day later. I understand that it is a very stressful and depressing time. Take care and I hope that you get good results. Please let us know how you go. Like you said, the odds are heavily in your favour, so I hope you get some good news soon.

[onthefly]

What a shock for you guys!
I think this is one of those times when you really want to get good clinical advice to help guide you and perhaps it might pay to seek a second opinion about what this means and what your options are.

[DADDY COOL]

For anybody with low papp-a and normal chromosome tests, consider thrombophillia. Apparently most doctors don't know about it and many premature babies, foetal deaths, retarded babies and cerebral palsy babies can be prevented. Read about thrombophillia here http://www.kofinasperinatal.org/8833...30005056A03A28

Also, a great article about low papp-a here http://www.theovalplanet.com/post.cf...-down-syndrome

We have something to cling to now. If our chromosome tests come back normal, I'm putting my wife on a plane to kofinasperinatal

I'm serously angry that we were not told about this and had our CVS 2 weeks earlier when they diagnosed the low papp-a

Please take action as soon as your result comes back if you get bad news

[melbel]

We had a low Papp-a of .24 on our Nuchal test and an overall 1 in 2 chance of DS. I have now have a very normal, very active almost three old in front of me. We also had a very good obstetrician who put us on low dose aspirin and clexane for the rest of the pregnancy and frequent monitoring. Good luck!