BW I'm sorry you're facing having a procedure which you find so anxiety-provoking. You absolutely should tell your dr about the level of anxiety you are experiencing, as it is a legitimate reason for the procedure to be done under sedation if that is what is necessary. FWIW I've had a bone marrow biopsy which is routinely performed at some treatment centres under only a local, but at my hospital a sedation is considered the minimum standard of care. So it could be that the liver biopsies are routinely available under sedation somewhere near you, and if it's not you should be able to request it any way. No doctor wants their patients to be distressed.