thread: Muscular Distrophy.. Genetics Q

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  1. #5
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    Mar 2008
    In the darkroom
    2,208

    X-linked recessive inheritance is when the mother passes on one faulty X chromosome (See figure below). The resulting child, male or female, has a 50% chance of inheriting the faulty gene but only the male can develop MD from it. Because the female child has two X chromosomes, one healthy X can override one inherited faulty X. In this instance however, the female child is still a carrier of the inherited faulty X and may pass it on to her children. The female child should have genetic testing to determine her status before having her own children.
    Ok so this is the one that runs in our family. So there is a 50% chance that I carry the gene - that is what I thought.

    So if I am tested and it is proven that I carry the gene, then there is a 50% chance of passing on that gene to my son who could then become sick with the illness later in life. Is that right?

    I looked up the gender selection/IVF and you obviously have to qualify to be able to have this done (in some places they have canned it all together). Even then - isn't that majorly messing with mother nature?

    On the flip side though - if I chose not to get tested and went ahead and concieved a boy, I would have knowingly put that child at risk.
    Last edited by Aimz; October 1st, 2008 at 03:45 PM.