I had male cats most of my life and when time came to getting another cat i went to the shelter and a beautiful female "picked" me.She was the best cat I've ever had...
not necessarily more or less affectionate than the males, but I think it was our connection that made her really special. I never had any issues with male cats spraying.
i'd say it doesnt matter so much apart from your own preference, but I'd choose a cat that would best fit in with your family and go with your gut.
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