We don't do time out as a general rule, but i had success with being very repetitive, i had a script, when she started it did a sudden "Please don't.. I cant understand the whinge voice, please use words" I would give her a few moments of attention to get her a chance to talk... then either listen to her talking normally or continue with what i was doing. It was VERY repetitive for a while.. and i was saying the same thing over and over, but it made a difference in a few days.. and now she knows the routine.