Hi, I was told the risk of miscarriage from a CVS was about 1% and less for an amnio. I was incredibly scared of this as I had just had a miscarriage a few months prior so was very scared to go through that again. I won't sugar coat it as I wanted honest information at the time as well. It was very painful - a big metal pole/needle inserted into my stomach and down into the uterus to get the chorionic villi sampling and then pulled back and forth till the got enough fluid. From memory you can cvs testing from 11.5 weeks till bout 14 weeks and an amnio is after 16. I think I was told if I was going to miscarry from it it would happen within 2 weeks. I had 3 days off work I think. You cramp quite badly after the procedure and are told to rest. It is a HUGE decision to make whether you have further invasive testing that only you and your partner can decide. For us we ummed and arred for weeks (as we found out at 9 weeks so had to wait) but in the end I knew I couldn't last a whole pregnancy mental health wise without knowing what we were up against!