I've hear the same things about panadol- that it can cause a highe risk of m/c but I think its just like many other medication in pregnancy- you asses the risk and judge for yourself. I mean doctors would prefer you take panadol instead of Ib profen and so on. If you're going to feel awful because you have a headache and don't do anything about it thats not going to benefit your health either. I was prescribed some pretty hefty painkillers last pregnancy for my sciatic nerve problems and Carter didn't have any birth defects. The other option is some natural remedies- just be careful not to use essential oils as many can be unsafe during pregnancy. For headaches try pressure points