Thing 1: find a liquid soap with moisturiser in it. This makes more of a difference on my hands than any other thing.

Thing 2: if you need to use hand sanitizer, get Aqium gel. It seems to have some kind of moisturiser in there & is nowhere near as drying as others.

Thing 3: have a try at using some coconut oil or similar overnight. If you can find some white cotton gloves, slather it on, put the gloves on & go to bed. I did this with my feet & it made a huge difference. Other oils to try include any mix of jojoba, almond or olive (if you can handle the smell).