Hi from another newbie I'd just like to say you have gorgeous taste in names! I love most of the ones on your girls list. My favourites are Sienna, Ruby and Olivia in that order; Esmeralda is a beautiful choice as a middle name and continues the tradition of naming after family members. I would suggest, out of the names you've chosen so far:

Sienna Isla
Ruby Isabella
Olivia Esmeralda

I would recommend against putting Isla and Esme together as you get "Isle Esme" connotations from Twilight... -_- ... combined with Isabella on your list, that could lead to Twilight-overload!

If you wanted some other choices, I love Charlotte, Chloe, Cassandra, and Grace/Gracie. All of those would sound lovely with Mia

Out of the boys, my favourites from your list are Lucas, Noah and Samuel, all with Jude as a middle name. You are lucky to have so many great names in your family! My children will be stuck with Barry and Paul as grandfathers... ho hum...