I wouldn't give panadol before, just have it on hand for after if it is required. I needed it once with one son, and once with the other son (can't remember which vax, I think the 4 months one). I prefer not to give medication that is not necessarily.

I think after the 2 months ones, both my boys slept a lot. They were more unsettled after the 4 month ones. But all kids are different.

All the best sweetie, I think the first time is the hardest for the mums!