Up until recently I'd use it at every nappy change as a preventative measure, but now I probably only do it every second change....DS only really gets a nappy rash around teething times though. DH never usually puts it on and tends to use talcum powder...but he doesn't change him that much anyway. But I'd always make sure that DS had nappy cream on for night time bed though (cause he sleeps through and usually has a very wet nappy the next day).