I think that it would definately make it flare, basically they are still horizontal and moving their stomach contents around a lot also, like the previous poster said usually when they are upright the reflux should start improving.

I would go back on the medication, if you go to your gp and just let them know the dosage that he was on before, surely he can write a script for the losec. You could try zantac if you wanted something easier to get than the compound. It may be enough to tide him over.

Also teething and illness tends to flare up reflux also.

With a routine, honestly I have tried it and nothing worked till he had the reflux under control totally, and then eveything came into place. Until then any type of sleep solution probably won't work properly.

Good luck with the GP, and you can always go back to the pead, I mean you are paying them and let them know what is going on.