with the background i have in medical science and biochemistry, i'll stand by my disagreement in this logic. there isn't going to be "left over" drug just because a person isn't as big. there isn't going to be different reactions based on size. it's all the OTHER factors that are going to come into it. you could put two people, same weight, same height, same activity level - and there reactions could be totally different based on genetic factors etc. size alone will not contribute to the reactions. i've watched two people with very similar builds, same job, same activity level etc take duromine for the "speed" factor. one was almost entirely normal to interact with - the other was very obvious he'd taken the drugs.
i know what you're trying to reason, but from a science perspective, it doesn't really cut it.
if you want to take it, then make the enquiries with the GP and see how you go - but don't try and convince yourself that it's ok for you at BMI 40+ because that's what it's designed for - and if you didn't weigh x amount, it wouldn't be ok cos it's not designed for that. don't try and convince yourself that you'll have less side effects cos your BMI is 40+ rather than being 30. the side effects for you will likely be much the same no matter your BMI. IF, however, your HEALTH changes, your side effects MAY change. it is unlikely though, that a healthier person at a lower weight would have MORE side effects from a medication (which is essentially what you're trying to justify from my reading).
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