I guess it depends on your coping skills.
I have 2 and it stretches me to my limit so I wouldn't try for number 3. Although part of me thinks a daughter would be nice I don't think it would be fair on my boys or DH or even myself to TTC a child when I'm fairly sure that I would find myself depressed and overwhelmed after its arrival.
If an oopsie baby happened of course I would find a way to cope but I would be struggling.