Minnie, aside from genetic testing, I'm not sure that it would help Have you had all the 'extra' tests like killer cells and what not? (not really sure about all those things...)
geez hun how frustrating for you, sounds like you need to get some blood tests done to see what your hormones are doing, i will keep my fingers crossed for you. in my last pregnancy the only symptom i had early on were the sore boobs like you described in your thread
madB: not really, after the 3rd miscarriage i had an ultrasound and a hycosy which were both normal, the fs also mention doing a lap but again i just don't think i need that because i can get pregnant so it doesn't seem to be a structural problem etc
chromosomal testing was something i had wondered about, how do they test that do you know ? i haven't had the NK test done, i guess thats also something to consider.......im just not sure what to think
There are threads on it - a few members have been tested and found it and went to have babies. I think it involves a biopsy of the uterine lining?
I think it would be worth looking further into. Would have to talk to the right doctor though - need someone who's familiar with this sort of thing.
HI Minnie,
just happened to spot your thread. I could probably give you a 10page thesis on recurrent m/c but A) you probably wouldn't want to know all that and b) I gotta get out of the house soon!! As you can see from my sig, I have lost my fair share of bubbas. Sounds like you have had most of the standard blood tests on yourself. These should also include karyotype sceen of you and your DH, although given you already have 2 children this is unlikely to be an issue. You could also have NK cell testing. This can be a blood test +/- a uterine biopsy (done on a specific day of your cycle). AS far as I know, you can only get these done "properly" in Sydney, There is a Dr Gavin Sacks there who has been doing a research project on it. I flew to Sydney (from Melb) for a day to have the blood test done and see Dr Sacks. My levels were high so I went on prednisolone for my next 2pregnancy attempts. The sceond resulted in my DD but I did m/c her twin. Who knows if the pred made the difference but I am currently also tring for no3 and certianly using it again.
Did you ever have any of your m/c "products" (sorry I hate talking about precious babies like that but can't think of a better term) tested esp for chromsomal issues?
I had most of miine tested but only one was actually abnormal (one trisomy 15 boy). If you did have any with chromosomal issues then the IVF/PGD option certainly could be useful.I won't go into a detialed speil but in a nutshell,They remove a cell from a day 3 or 5 embryo and test for chromsomal abnormalities so only "normal embryos are put back in.
I don't have PCOS but rarely, if ever, ovulate on my own so I need the ART to concieve. My DS was with OI/IUI. I didn't necessairly need IVF to concieve but did do it firstly to try PGD -no pg and not to many abnormal embies so we did do standard IVF again in the hope of picking a "strong" one. We did get sucessful with DD but I'm not sure IVF was really necessary -just something I needed to do at the time. Now trying for no 3 we are doing IVF again probably more because I am very nearly 40 and we also didn't want the risk of twins again - I just don't think my body is made for two and I couldn't face that heartbreak again. IUI for me carries far to high a risk of multiples because I have never just produced 1 egg.
Anyway, sorry to be so brief and jumbled with this reply but I am happy to answer any more questions (when I have some more time!)
thanks so much for your detailed post, i saw the specialist today, she basically said the miscarriages are just one of those things and she doesn't know why they are happening. i mentioned my list of questions, she didn't really believe in the idea of NK cells but said she would refer me to dr Sacks if i wanted to.
she suggested a lap saying 10-20% of people find a problem that way but i think that would be more for people who haven't been able to fall pregnant not those who can but can't hold onto the pregnancies.
i asked about ivf and again she didn't think that was a solution as the problem isn't getting pregnant and she didn't think it would change the outcome of the pregnancy
so the bottom line is i declined the lap and we are at the point of deciding whether to try ourselves or calling it quits
i have never had any of the pregnancies tested so don't know about chromosome testing but we are both going to get blood tests done just in case
so sorry about all your losses and good luck ttc #3
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Have you had all the 'extra' tests like killer cells and what not? (not really sure about all those things...)
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