HI Minnie,
just happened to spot your thread. I could probably give you a 10page thesis on recurrent m/c but A) you probably wouldn't want to know all that and b) I gotta get out of the house soon!! As you can see from my sig, I have lost my fair share of bubbas. Sounds like you have had most of the standard blood tests on yourself. These should also include karyotype sceen of you and your DH, although given you already have 2 children this is unlikely to be an issue. You could also have NK cell testing. This can be a blood test +/- a uterine biopsy (done on a specific day of your cycle). AS far as I know, you can only get these done "properly" in Sydney, There is a Dr Gavin Sacks there who has been doing a research project on it. I flew to Sydney (from Melb) for a day to have the blood test done and see Dr Sacks. My levels were high so I went on prednisolone for my next 2pregnancy attempts. The sceond resulted in my DD but I did m/c her twin. Who knows if the pred made the difference but I am currently also tring for no3 and certianly using it again.
Did you ever have any of your m/c "products" (sorry I hate talking about precious babies like that but can't think of a better term) tested esp for chromsomal issues?
I had most of miine tested but only one was actually abnormal (one trisomy 15 boy). If you did have any with chromosomal issues then the IVF/PGD option certainly could be useful.I won't go into a detialed speil but in a nutshell,They remove a cell from a day 3 or 5 embryo and test for chromsomal abnormalities so only "normal embryos are put back in.
I don't have PCOS but rarely, if ever, ovulate on my own so I need the ART to concieve. My DS was with OI/IUI. I didn't necessairly need IVF to concieve but did do it firstly to try PGD -no pg and not to many abnormal embies so we did do standard IVF again in the hope of picking a "strong" one. We did get sucessful with DD but I'm not sure IVF was really necessary -just something I needed to do at the time. Now trying for no 3 we are doing IVF again probably more because I am very nearly 40 and we also didn't want the risk of twins again - I just don't think my body is made for two and I couldn't face that heartbreak again. IUI for me carries far to high a risk of multiples because I have never just produced 1 egg.
Anyway, sorry to be so brief and jumbled with this reply but I am happy to answer any more questions (when I have some more time!)