I have been TTC for over 18 months (21 cycles) and have just been diagnosed with Hashimotos and mild lupus. My thyroid levels have stablised very quickly on thyroxine and I have just started taking prednisone to stop my immune system going beserko (my FS thinks that I may be conceiving but my body is rejecting implantation).

I have also been told to start progesterone pessaries as soon as I can confirm O, as apparently studies have shown that progesterone also helps suppress immune responses. I have got the pessaries from the chemist but are not really sure how long to use them for? If I start them 1dpo, do I only continue them on until about 12dpo, test if I am pregnant, then if not, stop them to bring on AF?

Also, the instructions with the pessaris say that they need to be used twice per day, I think my FS said use the pessaries at night.

If anyone has experience of using progesterone pessaries in the TWW, I would love some advice??