IVF with PGD #5

Jaki-is your AF regular and normally on time i am due in 8 day's so will be just behind you.

Motherhood look's like it is all going well for you i think you can get a little excited now.

Im usually regular. Whats most annoying is all the US appointments i made, i knew they wouldnt be accurate but didnt think i'd have to change them too much.
I rang my nurse today and even tho i said in the voicemail don't worry about calling back, it would have been nice if she did. So no advise there.

Good luck this morning Motherhood!!! Looking fwd to seeing results.
AFM- still waiting............ Having some cramps this morning but i had Indian for dinner so im not sure what kind of cramps they are! lol.
xx

Jaki - When I read your post I had a little chuckle to myself lol. I hope their the right sort of cramps. FX for you my dear :)

So, results are in. Made me wait a while today although, they were quite busy this morning at the clinic so it was to be expected I suppose.

So, estrogen was in the area of the low 2000's on Thurs and today it has doubled again so were in the 4000 range yay!!!! Largest Follicle was approx 22mm and then the range of the others was 19mm, 18mm, 15mm, 14mm and so on. Here is the good news, will trigger tomorrow evening for EPU on Tues at 7.30am!!!!

OMG it is actually happening I cant believe it. The Nurse told me to continue this evening as normal and she will call me tomorrow with all the definate details for my trigger etc. Hmmmm at least I will get to go to work on Monday and get it all sorted lol.

So after hanging up, I literally burst into tears after I got off the phone with her. I think it was my way of releasing all these hormones etc and in a way, breathing a sigh of relief. I know the EPU doesnt guarantee anything but it feels so much better than cancelling it all together like last time. Hmmmmm getting tears in my eyes now typing this.

Just now need to :pray: that more of my little ones catch up and just play the wait and see approach on Tuesday hey. FX for sure though. Wow, still hasnt sunk in I dont think.

Well best get back to it. Since we came home this morning have been cleaning the house bit by bit and taking my time. Now at least I know I will be able to relax after EPU without looking at a filthy house :D

Hope all is good with you girls. Thanks heaps for your support too and remembering me on my BT and US days.

Glad i could make you laugh!!
Such good new hun!!!!! Im so happy for you!!!!!!!!!!!
I'll be thinking of you on tues and can't wait to hear how many eggs you get!
xx

Hey motherhood what great news it looks like everything is going to be perfect this time around i look forward to see how many eggs you get on tuesday.

Jaki-no AF yet i hope it turns up tomorrow so you can have your blood test monday morning.

AFM-I'm hanging in there waiting for my AF it is due on friday i rang the pgd nurse to get some more day 1 BT forms as i used it and the spare last cycle anyway i had a talk to the nurse and i am not very optimistic regarding my E2 levels she said it could have been a one off or it could be i have estrogen dominance and it might not go down if that's the case i would not be a good candidate for ivf they could start a cycle with the high E2 but i would be at high risk of the cycle being cancelled due to overstimulation or that my lead follicle would be to big and take up all the meds preventing all the other follies from catching up so i would not have enough mature eggs at egg pick up and for PGD testing as you know we need lots so if this AF my E2 is to high that is it for us we both decided the waiting and stress associated with ivf is to much we will let fate decide and try natrually and hope and pray we are lucky 2nd time around anyway sorry to be a downer when you girls are doing so well i just never expected a fertile couple could not do ivf:cry:

Thanks guys!!! Was just saying to DH, maybe this is all meant to be this time. Only time will tell hey.

Ferrals - Dont be sorry. Were here to help support you in all this. We understand what your going through. I know exactly what you mean about a fertile couple not being able to do IVF though. Had the exact same thoughts last cycle and even this cycle when it seemed we were headed down the same path. Fingers and everything else is crossed for you.

Well ladies just a quick one.

Just did my trigger injection and compared to last time when we had to cancel our cycle, this trigger didnt hurt at all!!! Hope I did it right. Although, It hurt a little to start and then I slowed down how fast I was pushing it in and then the pain stopped.

Have to be at the clinic at 6.45am Tuesday morning. FX hey .

Hope all is well with everyone and you all enjoyed your lovely hot weekend.

Motherhood-good luck for tuesday hope you get lots of eggs.

Jaki-has AF turned up just yet?

AFM- waiting for my AF still not feeling real confident about the BT i am expecting the worst hopeing for the best.

Hi Ladies,

Quick post for you from my couch!!!

Jaki - Has AF arrived as yet??? Heres hoping she has sweets.

Ferrals - How about you. Has AF arrived for you yet too??

Please know ladies that I have my FX for the both of you.

AFM - So here goes - Up bright and early and into the clinic at 6.45am. EPU wasnt as bad as I thought and Im not doing too bad now either. So, all together we got 8 eggs. Of these 2 or 3 weren't quite mature but they said you never know. Fertilisation was to take place at 12noon today and we will get a call tomorrow to let us know how its all going. FX big time now. Grow little guys grow.

Best get back to resting. Oh also, ET should be on Sunday so now just have to wait till then.

Thats awesome motherhood!!!! Such a great result for you. I'll be paraying for great fertilasation report!

And Nooooooooooooo AF is still not here! I just can't believe it!! I even did a pg test which was of course neg. Im going to ring the nurse in the morning and see what she thinks, im also thinking about having accupuncture to bring it on.

xx

Finally!!! :leap:
AF is here, going for BT at 8am.
Fingers crossed.

Motherhood-almost there just got to get some healthy embies to TF and your in the TWW.

Jaki-YEH! finally mine is due in 2 days so if its on time and my BT is ok i will be just behind you.

Yahoo Jaki. Glad AF is here :D

FX Ferrals that you will definately, 100% for sure be just behind Jaki :).

Hmmm trying to feel optomistic about the call to day with the initial results re fertilisation etc but its hard to just "go with the flow". Back at work today and feeling surprisingly good. Im glad I feel good though :). Will be sure to keep you both updated.

Ladies, Just a quick one as finding it hard to contain my excitment at the moment and need to release in some way :D

Well just got the call, of the 8 eggs collected, 7 of our little darlings (or sprogs as Im coming to call them) have fertilised normally. One hurdle down and a few more to go. Next update on our little sprogs will be Friday. FX and a lot of :pray:.

That is AMAZING!!!!!!!!!!!!!!!!!!!!!!!!!!!!
How exciting!!!!!!!!!!
Good work
xx

Wont get my BT results until tomorrow morning as the pathologist decided they had to send it to sydney for testing. Im very annoyed. Also the nurse was a cow, made me feel stupid and made me cry.

Jaki-everything will be fine don't stress over some stupid nurse it will all work out.

Motherhood-7 out of 8 that is fantastic you will get a good number to test.

AFM- my turn next please i have waited patiently please let it be my turn.

Jaki - Any news of the BT results???? Am waiting anxiously to know.

Ferrals - I too hope its your turn next. :pray: :pray: :pray:

Starting injections tonight. Yeeeehaaaaa!!!!

Your next ferrals!!!!

Xx

Thanks girls i am so nervous no actually terrified that my levels will be no good.

Jaki- good luck with your injections hope you make lots of eggies

motherhood- i read a few of your posts in the other thread looks like everything is going perfectly for you.

AFM- as i said up top i am terrified that it wont happen for me i feel so left behind again i am also on another forum for PGD IVF and they are all cycling as well or are now pregnant and i am the last one yet to start i cant help but feel worried anyway i am happy for you ladies keep me informed and pray my AF turns up on time tomorrow.

AF vibes coming your way...

Here here Jaki

AF vibes your way Ferrals. You can have mine so that I wont get her :P

Only a quick one as not too happy.

Call from the scientist nice and early today with the following results;
- As we know, 7 fertilised normally
- 2 x 8 Cell Embies Grade 1
- 2 x 7 Cell Embies Grade 1
- 1 x 4 Cell Embie Grade 3
- 1 x 1 Cell Embie Grade 3
- 1 Embie that is degrading :(

So dont know that to think about all that. The thing is though, she had to add in that "not many embryos make it to day 5". That was the clincher for me. Way to make me happy NOT.

Motherhood it will be fine, out of that many fertilized some will have to make it to blast. Try not to worry too much.

AFM- had my first injection, all was good. Woke up this morning in a flooded house to my aunty screaming! So much for stress free Ivf. Having BT & US mon. Won't get results till tues morn.

X

Motherhood- 4 of them look like they are doing great so 4 out of 7 if they make it to blast is awesome.

Jaki-good to hear your 1st injection went well why is your house flooded? what happened?

AFM- just got back from acupuncture and i'm having AF pains now so pray they come to night and i can have BT tomorrow.

I was just thinking that too, 4 is awesome. I didn't even have that to start with last time!
Coffs is prone to flooding. Especially my aunts house. It all happened to quick in like 10 mins.
I'll be hopeing for you ferrals your levels are spot on.
X

Jaki-thank's and sorry about the flooding i was thinking burst water pipe or washing machine maybe but flood water from the weather is the worst.

AF still not here DH and i have had sex 3 times trying to bring it on but noooo luck why is it when your are all for it AF will turn up and ruin a romantic night and when we want it to come its' a no show.

Were now angry with IVF. Reason....... only yesterday, we found out and only by shear accident I might add (was calling the nurse about something else and she innocently said something assuming obviously that I knew) that they dont always test the embryos!!!!! I was like WTF!!!! What I was told was, If they dont like the look of the embryo because their looking a little shaky in that if they biopsy them they might inevatibly kill them doing so (Embryo isnt strong enough to withstand the biopsy and then transfer), they wont test for the Gene!!!! However the flip side of this is they still might be viable to return to my uterus and might still possibly make it resulting in a pregnancy. But this is where it gets interesting and we never ever knew that, we then have the choice to take the chance and implant one anyway untested!!!!

GRRR we have been under the impression the whole time that they are tested regardless. No one at any stage explained this to us. Having this information I rang the specialist to talk to him. So, the fertility specialist rang me today to kind of give me more info etc. He basically said that yes we need to wait and see tomorrow and if they dont like the look of them and their unstable so to speak, they wont test them however that doesnt mean we still cant transfer one back!!!!! He also said and I agree with him that if we didnt transfer just because they werent tested, it's kind of a wasted opportunity and or wasted embryos etc because we still have the kind of good only 50/50 chance that it would end up with the gene. If we were left with that option, that means at at 9 to 12wks pregnant, we need to go through pre natal screening to see if the baby has the gene, amnicentis type test. Hmmmm Not an easy decision as the specialist also agreed.

So, were not happy at all because were now in a situation where we need to make a decision NOW but not only that, DH is down the coast visiting his Brother in Bega and I had to explain all of this to him over the phone and we had to come to a decision. What makes us angry is that We totally understand that its not 100% guanteed and were not angry that they wouldn't test, were angry that we werent told this from the beginning. If we were told this, we may not have gone through with the IVF and tried our luck naturally instead, saving us a whopping $12,500.

After having a chat over the phone and weighing up the pros and cons, we agreed that should they tell us they wont test them but they will transfer, we will transfer!!! DH and I agreed in that we had already decided that should this go have been cancelled like the first one, which in the beginning it was looking that way, we would try naturally. That said, I also said to him that we are already committed to the $$$ but then I was like but if it wasnt tested and we put it back and the baby did have the gene, what a waste of $$$$. But then again, I said but there is still the chance that it wouldnt take even if it was tested and then $$$ and no success was just the same so its not a waste of money.

Hmmm not a happy day before final update!!!

Ferrals...... AF is she here????

Hope all is well Jaki!!

Motherhood- are you serious if thats the case we would be better off going naturally in saying that the scientist told us that untested embryos wont be transfered the way i will approach it will be test all that make it to day 5 if they don't survive testing then there is nothing to be transferred than we don't pay the bulk of the $$$$ why have untested embryos transfered and pay a fortune when you have a 50/50 chance the same as trying naturally i find that terrible we should have been informed about that from the beginning you have a lot to think about in such a short time just hope that your embryos are good enough to test i do understand what you are saying about having them transferred untested though you have come this far you may aswell finish the cycle.

AFM-no AF has not turned up i think maybe because my last AF was a bit longer and my estrogen was a bit high it will be a day or so late it should have been here today at the latest (my cycle is 28-29) today is day 29

Isn't the idea as simple as "If we know the test will kill the embryo then we won't do the test" - which saves the test lab some time analysing DNA from dead embryos, and you potentially some money paying for them to be tested.
The testing requires a hole to be drilled with a laser in the side of the embryo, and a cell or more to be sucked out. Even for promising looking embryos not all survive the test. I think you have to trust your lab here - they would love nothing more than to be able to pop a bad-gene-free emby back in to you, and they will be doing there darndest to make that happen.

Morning all,

Well had my Day 5 update from the Embryologist at SIVF. She let me know that they have had a look this morning and 3 of the guys are starting to form/enter the blatocyst stage however, they dont expect them to reach that stage until tomorrow morning. She also said that they like them to be hatching and bursting out before they do the biopsy. I suppose this is a good thing doing it that way.

So, that means another day of waiting. Frustrating. I need to have hope though that these guys will make it. The embryologist let me know also that they will check in on them again this afternoon and should anything have changed, will call and let me know.

:pray::pray::pray::pray: that all goes well and that if its meant to be it WILL be.

KMN - I know the PGD process however our lab does it a little different i suppose . Like I said above, they told me they like them to be hatching.

Hope everyone is well!!!

Ahhh Motherhood, it is alot to take in hay. I remember all those angry feeling of being missinformed. In the end i gave in and this is our final go with SIVF.
Stephen and i would defo use untested embrios as we cannot concieve naturally, if we could we would take the chance. The PGD for us is just another step we may make it through.
Your little guys are doing so well, i so wished mine had blasted last time. I remember being so mad on day 6, which was their last chance to hatch, because i felt we should have put one back earlier. So make sure no matter what one goes in tommorow. I will be much more assertive this time round. Im making sure i get my ET no matter what! And if this one doesn't work for us i will do regular IVF closer to home without the PGD.
I will be praying for your little embies.

Ferrals i hope she gets here soon for you.
xx

Hey Jaki,

Yup. we have decided that we will definately put one back for sure but the plan as Im sure you understand is to test if we can. When we weighed it up we felt that it would esentially be no different than if we tried naturally. And I really strongly agree with the FS that it would be a wasted opportunity if we didnt!!!!! There is every chance that if we put an untested back, it would be 100% fantastically healthy.

FX that the little guys are going great guns as we speak though.

Great to hear you have such a positive attitude! I can't wait for you to post tomorrow that you have had you ET, hopefully with a tested embryo.

AFM- starting to feel my ovaries changing. Have to hope not too drasticly tho, last time i looked 7 month pg and hyperstimulated! Looking forward to getting tommorows US & BT results on tues morning!
xx

I can't believe it still no AF WTF! never am i this late what is going on with me i am now feeling like there definately some higher power that does not want us to have a baby we have not one once of good luck since the day we had abbi's first U/S and got the bad news everything that could go wrong has and all we want is a break just a little help so somthing will go our way i am so ready to through in the towel i am way over this whole process it has been the worst 7 months of my life.
Sorry for the emotional me post i have just had enough

Aww ferrals she will come. Don't give up yet. Maybe you are already pg..??
Mine was soooo late too, I think it was a mental thing, as soon as I did a pg test she came!
(((((((Big hugs)))))))

I agree with Jaki Ferrals. She will come :)

So quick update for you. We have 2 that are hatching blastocycsts, Grade 2. So will get another call from the Nurse in about an hour or so advising when they expect the results in and what to do next I suppose. Only thing is though, FS doesnt work in Sydney today so will have a different doctor doing the ET.

Man O Man. Cant concentrate. Have been doing some reading of documents here at work and have read the same sentence about 5 times now. FX big time now that they come out clean!!!

Just a quick post before i take my two youngest boys to tutoring the witch has turned up so i will have my BT in the morning and results by 5pm tomorrow i don't feel real confident about it but we will see anyway be back later for persies