Hi Bec,

I think E2 is of the most concern due to risk of OHSS. With me, my clinic said that anything above 14000 is considered unsafe and at high risk. My second cycle my E2 reached 23,000 and was cancelled. Given I am polycistic, I have a tendency to produce lots of follies and therefore E2 tends to soar quite quickly towards the end of they cycle.
Are you doing IVF this time around instead of IVM? I am not sure if you are doing long down reg or antagonist cycle? Ihave done both and this time around I am doing an Antagonist cycle and have been doing daily jabs of orgalutran along with the puregon. This has really helped at keeping my E2 levels at bay. To give you an example. Last day before trigger 1st cycle I was 9000, 2nd cycle 23,000 (and they cancelled), 3rd cycle 14500 and this cycle on the antagonist with orgalutran 2800 (Yes I am still in shock), levels actually grew steadilly instead of the huge spikes on previous cycle.
I hope this helps somewhat. Goodluck with your upcoming cycle. You can always ask for daily BT so that your E2 can be monitored closely so that any adjustments to your FSH can be done if there seems to be a spike and concern for OHSS!
Mon