Kristy, the main drug I've had s/e from is synarel (alternative to lucrin). My first IVF cycle the synarel s/e hit me like a ton of bricks, to the point that I reduced my hours at work. But the 2nd and 3rd cycles were fine. I haven't tried lucrin, but the main s/e I've heard of from that is headaches. I've never had any s/e with puregon (this was my 6th cycle using it). The pregnyl trigger can give you some early pg symptoms. This is the first time I've used pregnyl for the trigger and the main thing I had was an aching lower back.

As for what the drugs do, the lucrin stops your body producing it's normal hormones. The puregon then replaces one of those hormones and stimulates the ovaries to produce follicles/eggs. The pregnyl trigger then causes you to ovulate and release the eggs. The trigger is timed so you are ready to ovulate just when you go into the EPU.

I've never done the lucrin injections, so I can't comment on those, but the puregon injections are a piece of cake. I'm a total needle-phobe and I have done all of my puregon injections myself. I take my time so I don't panic and do everything methodically. Others find it easier to get it over and done quickly. You just need to find what works for you.

I have more of a challenge with the pregnyl because my doctor wants it done IM (intramuscularly - ie in the buttock). DH has to do those for me. I think most people do the pregnyl in the belly though.

Baby2Bee, GL with your EPU today!

MrsP, GL with the transfer!

Sandy, I haven't had that. I'll be interested to hear what your Dr says if you ask?