you'll just have to use lucrin instead of synarellike have done this time round
Registered User
you'll just have to use lucrin instead of synarel
Moderator
Hi all,
Hopefully you don't mind me joining your thread! I am about to start IVF/ICSI (in about 2 weeks) and I thought it was a good time to stick my head in and introduce myself - even though nothing's happened yet!
As my signature says, I am 39 (40 in June!!!!) so this is kind of my last chance to get up the duff. I have a DD who is 8 1/2. I conceived her naturally.
I am currently on my 6th round of clomid. It has worked in that I have ovulated each time but no BFPI am skipping IUI and going straight to IVF/ICSI.
In terms of my "issues" I have PCOS, adenomyosis, and suspected endometriosis. I am overweight...okay, obese
I am with Melbourne IVF and will be doing an antagonist cycle on 262.5 of gonal f, an ovidrel trigger and crinone progesterone support. Not sure if that is normal or typical as I dont know anyone who has gone through IVF/ICSI.
Anyhoo....That is me (well, the reproductive side of me).
Hope to get to know you all better
take care
n2l
Registered User
Hi all,
Hopefully you don't mind me joining your thread! I am about to start IVF/ICSI (in about 2 weeks) and I thought it was a good time to stick my head in and introduce myself - even though nothing's happened yet!
As my signature says, I am 39 (40 in June!!!!) so this is kind of my last chance to get up the duff. I have a DD who is 8 1/2. I conceived her naturally.
I am currently on my 6th round of clomid. It has worked in that I have ovulated each time but no BFP
In terms of my "issues" I have PCOS, adenomyosis, and suspected endometriosis. I am overweight...okay, obese
I am with Melbourne IVF and will be doing an antagonist cycle on 262.5 of gonal f, an ovidrel trigger and crinone progesterone support. Not sure if that is normal or typical as I dont know anyone who has gone through IVF/ICSI.
hun this is exactly what i am doing right now except my gonal f dosage is 225
Anyhoo....That is me (well, the reproductive side of me).
Hope to get to know you all better
take care
n2l
Registered User
Hi girls. AF finally arrived, and next time she does I will be straight into a stim cycle. Can't believe I am back at it, but hey, ya gotta do what ya gotta do....!
Oneday - good luck with your new cycle!
Saffy - hope AF comes soon!
Jbm - hope she's gone soon!!
Katones - good Luck with this cycle!!!
Happybaby & Kass good luck to you both.
Nothing2lose - that sounds pretty normal, I am same age as you and last cycle was 262.5 and I think i got 15 eggs if i remember. Am increasing to 300 this cycle. Hopefully it doesn't overstimulate!!
Good luck to all.
BellyBelly Member
Hey ladies, started puregon tonight i always get so nervous doing my first one for some reason?
Kass the difference between down reg and antag is down reg supresses all your normal hormones and then you stimulate but with the antag on the first day of your period you start stimulating. And like Staffy said the only difference i know between them is that you get less but better quality eggs on the antag cycle and i think the antag cycle is easier as its a shorter one. My last 2 STIMs have been down reg and no success so i thought why not try something different and atleast it wont drag on as much. My clinic still does long down reg cycles but you need to use lucrin (injection form) which at my clinic is an extra $200. But i have heard there is no more synarel too.
Saffy goodluck with your FET XX
JBM i hope AF leaves soon for you xx
Nothingtolose, welcome
BellyBelly Member
I forgot to add yesterday that im so over the nurses and scientists trying to put their opinion in where they can!!! the nurse said to me yesterday, this concerns me that your having 2 blastie embryo's transfered when your so young (in front of everyone in the waiting room). I said iv discussed it with my doctor and he has ok it becuse this will be my 6th transfer! I wish they could be considerate of each individuals history before they judge. It starts to make me doubt my decision but i know its the right one and the more and more i think about twins i get excited about it, at this stage id be happy with what ever im givin xxxx
Registered User
Bit upset I had to remove my Pregnology signature - but I guess they are the rules.
Im bit sensitive at the moment with everything that has happened last week though. DH is home from hospital yestie and has a long grueling recovery of 3months in a neck/back brace and house bound. Obviously also this is going to suspend out TTC for quite a while
Welcome to the newbies and I hope your time in here is short, goodluck!
Ladies you asked about what was coming out in 2012. I didnt see it on the news, just going by what Ive been told from friends and family - its a breakthrough in America or UK and coming to us in 2012. Its something that helps an embryo to stick and gives an extra 40% chance of it sticking :-)
Moderator
Hi all,
The new drug is EmbryoGen. I saw a news story about it a month or so ago, didnt take that much notice after I heard it wouldn't be available until 2012. I hope to be UTD by then!!! FX
Here is an article which may help explain it...
"A University of Adelaide reproductive biologist has achieved a major breakthrough in IVF technology that is expected to help millions of women around the world who have suffered previous miscarriages after IVF treatment.
Professor Sarah Robertson, an NHMRC Principal Research Fellow and member of the University's Robinson Institute, has partnered with a Danish company to develop a product which improves IVF embryo implantation rates for some women by up to 40%.
In the world's largest clinical trial on IVF media, Professor Robertson and ORIGIO a/s a European company specialising in assisted reproductive technologies have shown for the first time that growth factor molecules are critical to ensuring optimal embryo development.
The resulting product, EmbryoGen, to be released in 2011, contains a signalling molecule called GM-CSF found naturally in the mother's tissues which protects the embryo from stress, making it stronger and more robust in the early implantation period.
The clinical trial, involving 1319 IVF patients exposed to either EmbryoGen or standard IVF embryo media, resulted in an average 20% improvement in embryo implantation rates at 12 weeks for all IVF women whose embryos developed in EmbryoGen. The effect is primarily due to benefits for women who had previously miscarried, who showed an impressive 40% increase in implantation success.
"This is a wonderful advance for couples undertaking IVF, particularly those who have previously lost babies in the first trimester," Professor Robertson says.
It is also the culmination of more than two decades' work for Professor Robertson, who based her PhD on the role of growth factors in healthy pregnancies and then worked with Swedish colleagues to explore applications in IVF embryos.
"This breakthrough has been 20 years in the making," Professor Robertson says. "It's enormously rewarding to see one's basic research translate into practical outcomes that will benefit so many families".
"From day one we went right back to the fundamental biology to see what makes an embryo healthy in its normal environment in the reproductive tract. We discovered that embryo is exposed to growth factor signals from the mother's tissues, which is critical to its optimal development.
"This is a major paradigm shift for reproductive medicine. All of the other ART companies around the world, along with biologists and clinicians in this area, have thought that embryos don't need growth factors.
"We have demonstrated through extensive animal and human clinical trials that the reality is just the opposite. EmbryoGen is not only completely safe and natural it contains signalling molecules that the embryo expects to find in the mother's body but our data from animal studies shows that it may also result in IVF babies that are larger and healthier at birth."
Professor Robertson says IVF children are often smaller at birth, sometimes leading to long term effects in later life.
"By adding back this growth factor and protecting the embryo from stress, the result should be babies that are of a similar size to those naturally conceived." The data on the perinatal outcomes will be available next year.
EmbryoGen will be launched in Europe and the Middle East by mid 2011 and in the USA in late 2012.
Bookmarks