Hi Big boobie gals! I too noticed my boobs were huge on puregon... and sore as all hell near EPU too, with even veins showing!!! I am usually and E so wasnt loving that part too much but at least they were more "full" and youthful looking rather than old lady boobs lol. Also I seemed to be more bloated in the belly, not just from growing ovaries as I'm sure a lot of it is fluid. Am starting crinone tomorrow so I will let you know how that goes.