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Thread: TTC & Taking Clomid &/0r Metformin ~ April 2007

  1. #91

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    Thanks for your replies girls. I think I'll just monitor my temps for this cycle and see how i go - next appointment with FS is a month away and I'll ask her about monitoring then.



    Good luck to you all.

  2. #92
    MUM2JADEN Guest

    Smile

    Hi everybody,

    Ive been posting on the LTTTC threads also. I'm on my 1st cycle of clomid at 50mg this month, I see my FS for an ultrasound on wednesday, can't wait.!! I have unexplained infertility, as I have a 2.5 yrold son who was conceived naturally first shot.
    Anyway, best of luck to everyone here, and it's good to know that people are getting pregnant and moving into the pregnancy threads, it's very hopeful...

    Kazz


  3. #93
    dream bub Guest

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    Hi Girls - Ive never posted in this thread before but just wanted to drop in with some news.

    Weve had 12 IVF attempts in 4 years - 9 of them Full stim & for some time now have been asking my Doc for Metformin. he reluctantly agreed to put me on it last cycle and I had a terrific result. Not only did I have 22 eggs at EPU but 11 fertilised successfully. All 11 grew to Blast stage - 9 were frozen and 2 were tfd last Friday so I am now in the 2ww. All Embies were great qualityh according to the scientist.

    This is the first time I have ever had more than 1 or 2 to freeze, and even then theres only everbeen a total of 4 the entire IVF journey.

    So full praise for Metformin - (not the horrible, nauseating side effects! - but its worth it)

  4. #94

    Join Date
    Mar 2007
    Location
    Ohio
    Posts
    18

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    Hi ladies,long time since I've had nothing to report until now and I have a few questions that I'm hoping you can help me with.
    First I'm still not O'ing not even after 150mg of clomid I'm on CD41 today and started provera to kick start me again however doc also put me on Metformin 500mg for a week 2nd week 1000mg then starting my 3rd week 1500mg. My question is how do I take clomid too? Do I take it? Will it be safe to take it? I have 2 refills I could get done either 100mg for 5 days or 150mg for 5 days. What exactly does the metformin do? Is it safe to take clomid with the metformin? I'm just full of ?'s as I want a baby so badly and I'm willing to do anything. SO....if anyone has been in my place I'd love some info please!My doc didn't say anything about the clomid just wants me to start the metformin. So I'm just asking what you all think. I know some take them both so I figure what will it hurt? Right???? Help me please!

    Thanks alot girl's!
    Hugs!!!!!!
    TR-8/31/06 right6cm-left5cm
    cycle 3/1/07 100mg clomid=bust
    provera on CD54 to get period.
    cycle 4/25/06 150mg clomid=bust
    today CD41 started provera to get period again and also 500mg metformin.
    been TTC since Oct.06 No luck any suggestions? Doc says since I'm a little on the "heavy" side he was putting me on metformin. 5'8" 235lbs.I'm a big boned girl..

  5. #95

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    Penny, the metformin is completely safe to take with clomid. It helps reduce the insulin resistance that causes PCOS. For some women it is enough by itself to get ovulation happening. Wasn't for me... but then clomid didn't work either. Only tried 50mg, the side effects were so bad I wasn't going to even think about trying a higher dose.

    If you're really worried, ask your FS. He may want you to just take the metformin for a while and give it a chance to work and then try clomid again.

    Even if clomid doesn't work, there is still hope! I'm currently using a drug called letrozole (brand name is femara) which works in a similar way to clomid, but uses a different mechanism in the body. It's not very common here yet, but seems to be much more common in the US. It has worked for me, worked really well in fact.

    Good luck with everything!

    BW

  6. #96
    MUM2JADEN Guest

    Smile

    Hi everyone,

    Saw FS other day and he did an internal ultrasound and he saw one large follicle ready to go any day now... feeling hopeful, no positive OPK yet, maybe later today or tommorow! Will check progesterone levels in a week and a half, I'm praying they are high enough, otherwise he will upgrade my dose of clomid.
    Positive vibes for everyone.....

    Kazz

    Last edited by MUM2JADEN; June 12th, 2007 at 11:29 AM.

  7. #97
    shell76 Guest

    Default Fertility Specialist questions....

    Hi,

    I am on my 2nd month of Clomid 50mg. I am currently seeing Mark Lawrence in Bentleigh but i am finding his quite frustrating in regards to getting answers to my questions. Does anyone else use him? Are you having the same problems? Maybe i am not asking the right questions?

    I just want some feedback on good fertility specialists......

    Thanks.

  8. #98
    MUM2JADEN Guest

    Smile

    Hi Shell,


    Sorry I cannot help you with the doctor thing as I am up in Cairns, but I think most doctors are a bit like that (elusive), it's rare to find one that will actually explain everything in detail. My doctors about midway - he tells me stuff and I just follow it up with the internet. I think it also comes down to a time thing - how busy they are!!!!!

    Anyway I'm 2 days DPO and have everything crossed!!!!!

    Good luck to everyone....

    Kazz


  9. #99
    MUM2JADEN Guest

    Smile

    Hi there everyone,

    I'm hoping somebody can help me with this query, I am 4 days DPO, on my first cycle of clomid at 50mg. Yesterday at 3 days DPO I noticed some brown streaks in my CM when I wiped and I also had to urinate many times during the night which has just come out of the blue....I urinated heaps when I was actually taking the clomid on days 3-7....but not since, until last night. Along with this I feel really hungry. Again I found brown streaks in my CM this morning. The thing is that it has all happened at once. Is it an effect of the clomid? Any suggestions!!!!

    Kazz


  10. #100
    newjob Guest

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    Shell76 - I was also seeing Dr Mark Lawrence and found exactly the same thing! I am now going to Dr Peter Lutjen in Brighton and he is fantastic! I can highly recommend him.

    I am taking my first round of clomid this month (25mg). Fingers crossed for everyone!

  11. #101

    Join Date
    Nov 2004
    Location
    Hunter Valley
    Posts
    499

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    BW - just noticed your BFP on your ticker. Congratulations!!!!

  12. #102

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    Thanks, Belinda! It's been a tough road - metformin, clomid... all failed... then IVF and not to be able to transfer on the fresh cycle because I was badly hyperstimulated... and then our first FET worked!! It's still not real to me yet...

    I hope more of the lovely ladies from here will be able to join us in PALTTC very soon.

    BW

  13. #103
    MUM2JADEN Guest

    Smile

    Congratulations BW, such exciting news that you are preggers.....I am finally in the second half of the TWW and get my progesterone results tomorrow...
    S many BFP's this month for the rest of us...

    Kazz

    Last edited by MUM2JADEN; June 22nd, 2007 at 11:43 AM.

  14. #104
    wrights Guest

    Default metformin question

    hi gals, just a question about metformin and pregnancy. i have pco, not the syndrome and after trying unsuccefully for months++++ and then suffering a miscarriage my gyn started me on metformin 2000mg xr. At the time he told me to take this whilst trying to get pregnant and then for the first 12 wks of pregnancy to help lessen chance of misscariage. Has anyone else been told this??? i was googling some further info on met formin and came across various articles that had different opinions on whether it should be taken when pregnant. Sometimes there is too much info out there, but i would hate to stop taking if it helped with misscarriage. My Fs is overseas on hols and i am sick of bombarding his receptionist with questions at the moment. I am due to HPT this week..... fingers crossed

    wrights

  15. #105

    Default

    I have heard the same thing regarding metformin... it does help reduce the chance of miscarriage and it quite safe to be continued up to 12 weeks.

    I'm 5 weeks today after my first IVF transfer... and I'm sticking with the metformin!

    One of my oldest and closest friends is an ob/gyn registrar - she checks all my meds for me against current literature and I'm assured that it's all ok... and my FS agrees.

    BW

  16. #106
    wrights Guest

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    thanks BW, i think its best to keep taking it too, it can take sooo long to get pregnant i would do everything i could to make it stick!!! thanks for the reassurance and a HUGE CONGRATS on you successful pregnancy - wishing you a very healthy and enjoyable 9 months - thanks again

  17. #107

    Join Date
    Nov 2004
    Location
    Hunter Valley
    Posts
    499

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    Wrights - BW is correct. The doctors are definitely recommending that you continue to take the metformin throughout the first trimester.

    I attended the POSAA National Conference in Sydney last year and Dr Warren Kidson gave a lecture on "metformin & pregnancy". Some of the statistics that he provided in the information we received were:

    -Vitamin B12 levels should be checked if taking metformin during pregnancy and you should generally stop taking metformin at 14wks, however if a GTT returns high it can continue to 24wks.

    Results from the following study:
    Gilbert C, Valois M, Koren G: Pregnancy outcome after first trimester exposure to metformin: a meta-analysis. Fertil Steril. 2006 Jul 28: 8 separate studies included for analysis.
    - Metformin taken in 1st trimester gives 57% protection compared to pregnancies without Metformin.
    - Malformation rate in the disease-matched control group was approximately 7.2%, statistically significantly higher than the rate found in the metformin group 1.7%.

    Hope that helps.

  18. #108
    MUM2JADEN Guest

    Unhappy

    Hi there everyone,

    Congrats to everyone for there BFP's this month, it's a fantastic result.
    Can anybody tell me if they have had a period come really early on clomid...I'm on CD 27 and am starting to bleed and had mild cramps yesterday....This means my cycle would have only been 26days which it's never been in my life!!!!!I've deducted that I would have only had a luteal phase of 12 days!!!! WTF......My cycles before the clomid were 30-33 days long. I don't know whats going on.....

    Kazz


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