OP what sort of work do you normally do? There are definately legit jobs you can work from home, but a lot of the E-bay selling type jobs really only make a bit of spending money (well as far as my friends have found).
I work in govt. and you can sometimes apply to work 1 or 2 days from home but of course that depends on what your job description is. I have heard that there are legitimate jobs such as medical typing that you can do from home but you would need to know somebody who does it to point out the genuine jobs from the scams.
Good luck!