Our PAPP-A was 0.28 and our combined risk came back at 1:2 so as high as you can get, basically we had a fifty fifty chance of down syndrome. Our CVS was normal and we have a beautiful perfectly healthy baby boy sleeping in the pram next to me to show for it.
Low PAPP-A can also be an indicator of possible heart issues so you will need to have a detailed morphology scan at 20 weeks or so to rule this out...ours was clear. It can also be an indicator that the placenta may no thave attached as well as it should have and this could mean you have a risk of possible IUGR or small for dates baby so you will probably need to have a few growth scans later on to keep an eye on this. there is a small body of research that seems to indicate that taking low dose aspirin and clexane injections can improve blood flow to the placenta and improve baby's gorwth rate...we did this as a preventative measure after consultation with our specialist obstetrician I gave birth to a 4.4kg bouncing baby!
I guess our baby is proof that all of things that could go wrong are just possibilities and things to look out for......they may never happen....in our case we were very very lucky and very blessed that nothing happened.
good luck.....I know how scary that wait for the CVS and then the results is...I will be thinking of you and praying for a good result.....just try and think this way you may have a 1 in 29 chance of a down syndrome baby but you have a 28 in 29 chance that bubba will be perfectly normal......
Last edited by melbel; May 16th, 2010 at 02:39 PM.
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