Belle, with my first pregnancy, I reduced my dosage of metformin from 1500mg to 1000mg at 8 weeks. At 8 weeks 5 days we discovered that the baby had died... at 8 weeks.

Too much of a coincidence for me!

With this pregnancy, under the advice of Dr Gavin Sacks, I was to stay on 1500mg until 12 weeks and then stop. I actually ended up slowly weaning off from about 14 weeks and stopped it completely at 17 weeks. Baby is happy and healthy and has no problems at all.

There's been several studies that have shown that metformin in the first trimester can help prevent miscarriage for women with PCOS. I haven't seen said studies, I've just been told they exist.

I ended up having one FS say stop, another say continue, my GP said stop, one OB say it's ok to be on the whole way through, and my OB was happy as long as I stopped after first trimester... Not even the medical profession can agree on the benefits or otherwise!

BW