thread: metformin/diabex in pregnancy?

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  1. #1
    Registered User

    Dec 2005
    6,706

    Belle, with my first pregnancy, I reduced my dosage of metformin from 1500mg to 1000mg at 8 weeks. At 8 weeks 5 days we discovered that the baby had died... at 8 weeks.

    Too much of a coincidence for me!

    With this pregnancy, under the advice of Dr Gavin Sacks, I was to stay on 1500mg until 12 weeks and then stop. I actually ended up slowly weaning off from about 14 weeks and stopped it completely at 17 weeks. Baby is happy and healthy and has no problems at all.

    There's been several studies that have shown that metformin in the first trimester can help prevent miscarriage for women with PCOS. I haven't seen said studies, I've just been told they exist.

    I ended up having one FS say stop, another say continue, my GP said stop, one OB say it's ok to be on the whole way through, and my OB was happy as long as I stopped after first trimester... Not even the medical profession can agree on the benefits or otherwise!

    BW

  2. #2
    Registered User

    Dec 2006
    In my own private paradise
    15,272

    Belle - my FS told me last week to continue taking met through the first tri - by the time we're ready for me to stop it, i'll do as BW has done and wean off it over a couple of weeks

  3. #3
    Registered User

    Oct 2005
    Cherry Tree Lane
    1,108

    i stopped min a 5 weeks miscarried at 6- dont stop taking it until 2nd tri IMHO

  4. #4
    Registered User

    Jul 2008
    Melbourne
    502

    Thanks girls. You'd think the dr's would get it right! I honestly don't want to reduce it early when I do fall pregnant Have heard too many cases of early mc for it to be a coincidence.

    What dose are you at BG?

    BW & LSK - I'm sorry you had to go through that Congrats on your pregnancy BW! I hope it's a H&H one.

  5. #5
    Registered User

    Dec 2005
    6,706

    Belle, I think it's because it's only recent research and it hasn't necessarily filtered all the way through to all doctors.

    BW

  6. #6
    Registered User

    Dec 2006
    In my own private paradise
    15,272

    Belle, i'm on Diabex XR (extended release) 1500 per day - i was on the same dosage as you but because i had such dire response to it (i was really really ILL!), i was swapped to XR.

  7. #7
    Registered User

    Jul 2008
    Melbourne
    502

    Thanks BG. I think I will chat with my ob when the time comes.