Just thought I'd add this in case anybody gets confused ... false positives are guaranteed at being close to a certain rate for screening tests like this. For example, they will pick a ~5% false positive rate for a ~90% detection rate. Depending on the exact method used, thats about the rates you get for NF+bloods. They could reduce the false positive to say 2% but the detection rate will drop to say 65% (last figure a guess just to illustrate what I'm saying). A 5% false positive means 5% of *all* women screened will get a false positive - so 1 in 20 will get a positive screening result even though most of these will be fine. (It doesn't mean 95% or even 5% of positive screening results will have a positive CVS/amnio result - its down around 1% somewhere).





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