It's reassuring to hear I'm not alone - thanks for the replys girls. It came again at 3pm on the dot. I took Panadol just as I first felt the twinges and it seemed to not get to the unbearable stage. I preach this to all my customers (I'm a pharmacist) to stop the pain before it get too bad cause by then it's usually too late. I just hate taking anything like you Alison. But in the long run if it means I can get through the day - it's definately better to take them. Why do I only get them late in the day though? I figure it's all hormone related. Just when the MS had eased too, now this...... When do I start glowing?