My midwife gave me a paper about RLT and it says to start no later than 32 weeks for best effect, I assume you don't want to start too early though but it doesn't say the earliest week to start. 2400mg each day in tablet form and 4-5 cups a day in tea form. Unfortunatly he didn't give me anything on EPO so I am taking 4 a day orally and 1 internally at night although I tried 2 last night, I found a lot leaked out with 2 and none leaked out with one so my guess is that one is just as effective as 2. I hope so anyway as I am ready to go now, I can't cope any longer!!!