IVF with PGD #5

Welcome to IVF with PGD forum. This forum is for those that are undergoing IVF with Preimplantation Genetic Diagnosis..

This forum provide a space to discuss the issues associated with undergoing IVF with PGD. Please keep the discussion relevant to the forum topic. If discussion becomes more general in nature you will be directed to the LT or LTTTC/AC general discussion threads.

Your Moderating/Admin team for this forum are as follows:

Sarah_H Admin

Lenny Moderator
marcellus Moderator

To contact any of the above, please see this post.

If you have any issues/problems with this forum feel free to email any of the above moderators who will be happy to assist you. All emails will be treated confidentially.

The last thread is HERE

Ferrals we have the same doctor!!!!!!!!!!!
I wonder if Motherhood's doctor has the same accent???

I realize you have been bombarded with information, and options and doubts and not alot of hopes but just take next month as a whole new experience, fingers crossed its all good then for you, and we will be cycle buddies!
Do something super fun over the next month.
xx

Evening,

Just quickly, I have a male FS so me dont think we have the same FS :).

Night night!!

Thank's jaki-i am feeling better we have decided to go back on the vitex while we wait to try and level out my estrogen and progesterone and i will stop it before my BT next month my acupuncturist(spelling) said it wont do any harm but i feel that it's just the way my body is i alway's ov early and i have a high sex drive (side effect of high estrogen) so we will just wait and see what next BT is and hope they start, me what day in nov is your AF due mine is the 6th which if i fall preg would make me due the exact same day abbi was due i wonder if it's an omen or somthing anyway it's cool we have the same doc we might bump into each other in the waiting room's.
So i have decided to just relax and try to get my estrogen to behave if it's still high we will just do what the doc say's until this year run's out then we throw in the towel and try the old fashioned way and pray that we pass on our good gene's.

Mine is actually due the 29th or 30th Oct, so i'll be a bit ahead of you. But might end up in clinic around the same time if i make it back for an ET, fingers crossed.
Glad you are feeling better and have a plan.
xx

Morning all,

Quick post to update.

Had my first BT this morning and picked up my FSH injections ready to start on Sat. Still no AF though so FX she arrives some time today. Anyone who has her, please send her my way, pretty please.

Nurse told me quickly this morning that I will be on 375IU of Puregon. WOW is what I thought, such a big difference from my first cycle which I was started on 175IU and ended on 350IU. She only told me because I commented on the amount of Puregon 900 I was given :). Lets say my little blue esky is over flowing!!!!

Just will not try and sit and wait patiently for the Nurse to call this afternoon. Hmmmm hurry up afternoon and FX an :pray: AF arrives too.

Wishes and luck to all with where ever your at! Know that Im thinking of you all!

Send AF vibes your way!!!!!!!!!!!
Thats a HUGE dose but i quess they want to fill you up with follies this time!!!!!!!

AFM- im running right on schedule, started ovulating today so in two weeks time im on my way!!!!!!!!

xx

Quick one ladies.

DING DONG AF Calling!!!!!:clap:

Jaki - your AF vibes must have worked. Thanks :)

Yay, she is here so full steam ahead and on track to start my FSH on Sat. Nurse confirmed again that my dose will be 375IU (Hello hormones!!!) with a BT scheduled for next Tues.

Have put DH on notice about the high FSH dose and unlike last time where I didnt really feel a thing the whole time nor was I really moody etc, this time might be different lol. We will wait and see hey.

Almost home time YAY. Have a good weekend one and all!!!

WHOOOOTTTT!!!!!! Good work!!!!!
Enjoy your mood swings, lol.
Keep us posted.
xx

Ladies its very quiet in here!

How are you going on all that FSH Motherhood?

Morning,

Well where to begin. AF is just about gone and has been extremely well behaved which was great. Lucrin injection dash from my cousins wedding Friday night went well which was a relief. Started my Puregon injections Sat night at the lovely dose of 375IUs. All good there so far, no real side effects to speak of but I suppose, early days right??? Not so sure that no side effects is good though.
Had my BT bright and early yesterday morning to check on my estrogen levels and for the FS to see whether we need to increase or stay on the same dose of FSH. However, as we speak, I still don't have my next lot of instructions (I do normally get my next lot of instructions around lunch time the day of the BT). So I called my nurse at 4.50pm yesterday all worried as to what was going on. She apologised so many times and explained to myself that they haven't been able to get a hold of my FS at all :(. All I could assume was that he has been busy in surgery etc understandable but frustrating none the less. So had a quick chat with the nurse about my levels. Nothing official so to speak but she was trying to help me given the situation of not being able to contact the FS. I let her know that I was anxious to see how I responded on this dose of Puregon given that It was such a high dose. The response I received I didn't like and got me worried. Nurse let me know that I responded pretty much in the same way as my first cycle and then I was only on 175IUs of FSH. She told me that my estrogen levels at my BT last Thurs was 119 and then yesterday morning, was only slightly increased to 143. Not much difference if you ask me, especially for a daily FSH injection of 375. I have tried to rationalise it all, telling myself that I take my injections at 9.30pm and my first one was Sat night and so by the time BT rolled around on Tues morn, technically it was only 2 to 2.5days of FSH. So am hoping against hope it goes up. Last night though I hit the internet and looked up about the estrogen levels and now have myself in a state of worry. Im worried to say the least that things are going down the exact same path as last cycle. Is someone upstairs trying to tell me something??????
So spoke to the nurse this morning just to see if there is anything else I can be doing to get my levels up and unfortunately, theres not. Just have to hang here and wait. All I can hope is that they go way up before the next BT and possibly my first US. Nurse also confirmed that my FS did contact them there late last night after they had all gone and so will be speaking with him today and then calling me with my "official" next lot of instructions (we both agreed after not hearing from FS last night to just continue on the dose of 375IU's). Nurse also assured me that she will have a good chat with FS and I have asked her to let him know that I want to know if there is anything else I can do.
I just don't understand why this is happening. Im even doing acupuncture on a weekly basis and have had about 6 treatments now. Surely things should be better than what they are.
Have had the worst night, didn't really sleep much and now have the sorest eyes and head because of the crying. Almost lost it on the phone too this morning when talking to the nurse. I hope that these emotions are an indication of my raging hormones. DH even told me last night when laying in bed awake that If this one doesnt work, we will give going natural a go. Its only a 50/50 chance the baby wont have his gene though. So who knows :( :( :(.
Will be sure to let you know what happens when I get my call later.

oh im sorry your all worried. Hopefully your levels will rise and rise.

I know how you feel about the 'person upstairs', between my genes and my DH's sperm i wonder sometimes too.
As for giving it a natural go, some ppl frown apon it but honestly what are we supposed to do??? The most natural feeling for a women is the yearning to mother a child and it does not go away! And considering this technology is fairly new people have always just taken the chance. In my family i have seen bad cases, mild cases and no cases. Its a hard thing to do but i would do it if we could.
Have you had a meeting with Sydney genetics in the same office as SIVF? He is great and i think they can do a test on the baby at about 18-19 weeks or so.

Hope you feel better soon.
xx

Just an update as finally got my call from the Nurse. Have to go up from 375IUs to 450IUs with an US and BT on Sat morning. Hmmm doesnt make me feel any better but what did help is that my nurse sensed that I wasnt all that good when she told me and actually called me back to have a chat and make sure I was as ok as I can be.
Like I told her, IVF is hard but when your there for genetic reasons and genetic reasons only, when you have these issues, it makes it twice as hard.
Heres hoping my levels go up and up and up. Got nothing else to do but FX and :pray:.

Motherhood- your having the oppisite problem to me i have plenty of estrogen to spare i wish i could give you some of mine and i know what you mean we can have babies naturally and have to do pgd for genetic issues only and when these stupid problems make ivf hard it is even more stressfull Dh and i have decided if we cant start next month we will go back to try naturally we have a 75% chance baby will be ok and they can test with CVS at 11-12 week's i do know apples and tomatoes are high in natural estrogen google foods high in estrogen i did so i can avoid them eat lots of chicken full of hormones it might help god i hope this cycle will be successful for you.

AFM- November is not to far away but i'm not real optimistic something is going on in my body my FS said my day 1 BT showed i was fertile and would ovulate early but today is day 12 and my opks are still neg and i havn't felt myself ovulate yet so much for being early i don't know what is going on this has never happened i always feel myself ovulate between day 11 and 14 and my opk's always show a really strong line from day 10 so i think i will miss out on November i am gearing myself up for a sorry you can't start your ivf cycle from the pgd nurse that way i wont fall to pieces when it doe's happen.

Sorry in advance for the no personals.

Am still feeling quite down and depressed about my estrogen levels and the up in Puregon from 375IU to 450IU.

Still no side effects what so ever other than being extremely tired and having a slight headache. To be honest, am putting these feelings down to the cries I had yesterday and even earlier today in the toilet at work (a colleage was rude and that got me started).

I have a question. How on earth can I know that my estrogen levels are going the way they should be without having my BT or US till Sat morning. I wish there was a way I could find out just to put my mind at ease. Im not feeling very positive at all and this will only be my first US . Wish I could go back to cycle number 1 when I knew nothing at all.

Hmmmm what to do ladies, what to do. I think I need to talk to the counsellor.

Forgot to add, not even my lovely week long holiday to Fiji I booked yesterday is helping to keep my spirits up. And its not that long till we go either .

Motherhood-I wish i could help i have no clue when it come's to the estrogen while on the meds but i can understand how you are feeling i am terribly worried i wont even be able to start a cycle due to my levels being to high.
And i would talk to someone my DH asked me if i would see someone to talk to as i am not copeing real well at the moment i rang him in tears today because my day diddnt go to well it must be thursday's i struggled all day at work on the verg of tears you know when you can't even look at someone cause you will burst into tears my day started with a txt from my best friend to say that her waters broke and the baby would be born today then when i was at work a workmate told me the his ex partner who has 5 children to different men and left him after their son was 6mths old and fell pregnant with her 6th after a one time brief encounter with my work mate on an access visit with his son is having a girl so that was enough to send me to the toilet for a cry then to top it off another friend who has 2 children 1 to ivf and another natural told me she is 3 mths pregnant and she is 39 and not sure she really want's to have another baby so that tipped me over the edge now i am at home waiting for a txt to tell me what she had and my cow of a SIL is due tomorrow so i am feeling really down today i feel like i will never have my DHs baby my time has run out and this stupid gene wont let us have our baby i want to go to bed and forget the whole day.

I know exactly what you mean Ferrals. I had a cry myself in the toilet too today.

Feel better soon ok and know that were here knowing/understanding and feeling the same things.

Motherhood- good luck for tomorrow i am not working so i will be waiting for you to post your levels and follie count my fingers are crossed we need some positive news.

AFM- i did my OPK early today and it was still neg so i went to see my acupuncturist(spelling) and went over possible reasons for my high estrogen and not feeling myself ovulate last month which has never happened before anyway she did some extra things to me to help destress and gave me extra needles to bring on ovulation by the time i got home this arvo after picking up the kids i have have slight period type cramps so i went and done 2 more OPKs and got a real strong positive line on both so thank god my body is working right on que so much for the FS saying i will ov early i am on day 13 so i should ov tomorrow what a shame we have to avoid getting pregnant until this next BT but i am happy that i am back on vitex and my body seems to be doing what it is supose to do God i hope i get to start next month i am prepared to get the bad news as this whole thing has been bad news from the begining i told DH if we cant start next month that is it for me i wont go the ivf way we will do it the natural way and if i get pregnant will test the baby at 12 weeks i just cant handle that we cant do anything because of my hormones when all this time wasted (6months) we could have been pregnant by now if i had any idea that this could happen or cycles be cancelled i would have still tried naturally as i am 36 in 5 months the clock is ticking.

Jaki-what is happening with you anything yet or are you still waiting for AF to come.

Thanks heaps for your wishes Ferrals. I too hope we have good news. Will definately be asking all the questions re follie count etc tomorrow. Normally I just take what they tell me.

Have been trying to see if I feel any bloating etc but I think I dont feel anything. Maybe, just maybe slight ache type feeling might even say very, very slight period type pain. SO Im hoping that Im really feeling these things and not just imagining it because thats what I want to feel. We will see tomorrow wont we.

Thanks again for the wishes and support. Will definately be sure to post on here my details and like I said, will be drilling them tomorrow for all the details. Might even arm DH with a pad and pen at the US and take down the exact same details lol.

Afternoon all,

Sorry no personals. Am feeling rather upset, have had a cry and just dont know what to do. I need to vent a little.

So,DH and I travelled bright and early this morning for my first US and 3rd BT. All was ok good with that, just had to wait for my "official" results phone call. Noted at the US that the follicles they did measure were quite small with the largest being approx 10mm :(.

Anyway, got the call from the nurse. She let me know that she had spoken with my FS who wants to push on with this cycle (gee sounds promising..... not). He has asked that I keep taking the 450IU of Puregon and the 10units Lucrin each day and I need to go back in on Tuesday for a BT but no US this time hmmmmm. Nurse also told me that my Estrogen levels had increased slightly (Tues was 143 and today it was at 360) but still down on where they would really like them to be at. Nurse also told me that my uterus lining is at 6mm so all good there and that I have 9 follies however all were smaller than 10mm :(:rolleyes: She also said that she was waiting for FS to look at my FSH levels from the BT. Not sure what she meant by that but Im sure it didnt matter.

To say im disapointed with those results is an understatement. I have a feeling that were headed down the same path as cycle number 1 and that is cancellation due to poor performance. Im sorry If Im affending anyone but this just isnt fair. Why am I not responding to my Puregon shots. Thats one thing I just need to know is why? Is there something else medically wrong with me that we have missed and I need to have it looked into. Not to mention, If we were to stop IVF and try naturally, what complications would we have then??? I thought IVF was to help, not hinder. Its just not fair.

Havent mentioned to DH yet but am seriously thinking of cancelling and giving up (I know this is only number 2 but can you blame me when it all seems to be tracking in the exact same way. I have even gone for Accupuncture for this session and I am of the opinion at the moment that I dont think it did diddly squat for me). I dont know that I can keep going knowing the information I know from my failed first cycle and what it is im being told now. I feel like I already know where this is headed and Its just not fair at all.

Sorry for the very big me post. I just dont get it at all now. WHY body, Why are you doing this to me!!!!!

Aww Motherhood i am so sorry things are not going to plan but it isn't cancelled yet so hang in there.I feel the same way i thought seeing we have normal fertility and are only doing ivf for genetic reasons i assumed it would be easier for us and to find out that fertile people might not be able to go through ivf is distressing and i also thought about giving up on ivf and trying naturally as i feel the ivf road is more stressful because if we fall pregnant naturally it's one test at 12 weeks to get the all clear but with pgd its if you can start a cycle and then if its not cancelled and if you get enough eggs and then if they fertilise and then if they make it to day 5 and then if they make it through testing and are uneffected and then they have to stick PWEEEEW! no wonder we are stressed with the whole process i have decided we will give pgd ivf one go hopefully (next month) if we cant start or it doesnt work that is it for us our relationship is to important and i can feel the stress and i dont want it to ruin it all i can say is i am praying for you and i hope it all works out.
I am terrified of my first BT in two weeks we need some good news.

Just a question last AF when i was waiting for my BT result on day one i opened my puregon cartridge and put it in the pen and put the needle on to get it ready seeing as i didnt end up useing it i have read once it is opened you have to discard it after 28 days i took the needle off straight away will it be still good to use or should i just use a new one when the time comes

Hey Ferrals,

Not sure, It might be ok but just to be on the safe side, use a new one!!!!

Hi ladies, sorry for the absence. No reason just busy with work and planning.
Sorry you are both feeling down, Motherhood please don't quit this cycle till the fat lady sings, 9 follies is way better than last time is it not? And 10mm will keep getting bigger, try to be positive. If i were you i'd keep going, it will be interesting to see what comes out at EPU. You may be supprised.

Ferrals i hope you are on track for this month and we will be cycle buddies!

I totally understand you both wanting to try naturally, if we could we would be too.

AMF- Leaving the sticks on mon morning, going home to Coffs Hr to relax and wait for AF, then all going well my cycle will start. :pray:

Hey Jaki,

Thanks for the well wishes. Am feeling a little better this morning about it all. Yeah 9 follies is ok. I think in the end though we only ended up with 1 at the right size and another knocking on the door so to speak so a potential 2.

Who knows what will happen. Heres hoping the FS sees what he likes at the next BT on Tuesday. I have everything crossed for us but I suppose DH is right, just have to wait and see. Grrrr frustrating. Am thinking of calling FS tomorrow to get info straight from him. Hope Im allowed to call him because I think I just need answers.

Yeah, give him a buzz, that is your right!
I can call mine anytime, she even calls me. (she would be in the same office as yours.)
I have heard if ppl getting only 1 mature egg and passing PGD and getting pg, i realise that is really rare but my point is miracles happen.
xxx

Motherhood-GOOD LUCK TOMORROW-i have my fingers crossed i start work at 2 tomorrow until midnight so i will have to duck home on my dinner break to check for your post :pray:praying for some good news

Thanks Ferrals. Will be sure to post as soon as I know :)

Already had the water works again tonight. Didnt help that there was a cute little baby on my hour long train ride home from work!!!!

I am hoping for good news but at the same time, have also been telling myself that I think it will end the same as last time. We will see hey. Im guessing that because tomorrow is only a BT and not the usual duo of BT and US it might be the tell tale sign of whether we continue or not. Did ask the nurse today when I was talking to her about time for another!!! Sounded promising but up to FS i suppose.

Will keep you posted. Hope all is well with the two of you as well!

Hey ferrals, have you noticed that our FS has moved to george st and out of the SIVF building? Whats up with that?? I liked having everyone in the one place!

GL with you BT Motherhood.FX!

xx

Jaki- No! i wasn't informed that's nice sort of makes you feel unimportant not to notify us i hope they at least have the same number so i can contact her if i want to.

Motherhood-my fingers and toes are still crossed for you.

AFM-10 days until AF pleeeeeeeeeeeeeeeease give me normal hormone levels.

I know i was supprised to... i sent her an email and when she replyed at the end it was like, oh by the way take note of new contact detail... new email, new address and new phone/fax numbers. Even her receptionist has a new email, which i was annoyed about as i had email her asking for a note to fly with needles and never heard back from her. Now i know why. When i speak to my nurse next im going to ask what the go is.

Afternoon all,

Just a quick one to vent my frustration at still waiting for my BT results from this morning. My stomach is doing somersaults with what the results might possibly be and where it leaves us with cycle number 2. I know that I need to wait, its just hard and this isnt even the 2ww for me lol.

Well back to waiting for the results and the answers to my questions I armed the nurse with yesterday for when she speaks to FS today!!!!

Will update later my results. Thanks again for all your support ladies.

Afternoon Ladies,

Well here we go. Just got the call from my nurse.

FS is happy with the results from todays BT as it shows im finally responding to the 450 Puregon YAY! Nurse told me that my estrogen level at todays BT was 1195:dance:. Previously at Sats BT it was 360 and before that it was at 143. Need to keep going with the 450 Puregon and then back in for a BT and US on Thurs morning. Let the nurse know too that I have been feeling a little achy and period pain type feeling the past couple days or so and hoped that it was a good thing. She confirmed that yeah, it is a good thing. With my estrogen levels, we now just need them to keep going up and up.

I cant describe how happy Im feeling now and I feel as if a weight has lifted off my shoulders however as I have just told DH, I cant let myself get too excited, need to calm down and see what happens and go with the flow.

Nurse also let me know that she discussed with the FS what steps we can take to get around the slow response. His response was that in possible future Stim cycles we would start with the Puregon first and then bring in the Lucrin. Obviously I dont need too much surpressing. Oh well we will see hey.

Am so happy now. Bring on Thurs and Body/uterus, you are to be on your best behaviour all the way right to the end with our BFP :D (Wishful thinking)

Hope all is well with you ladies. Best wishes for where ever your currently at :)

YAAAAAYYYYYYY!!!!! So happy for you! :clap: Awesome news, Im so excited to hear your results on thurs! Good luck, i'll be prayin for you!

xx

:

---

Afternoon Ladies,

Well here we go. Just got the call from my nurse.

FS is happy with the results from todays BT as it shows im finally responding to the 450 Puregon YAY!

---

Great news!

take care,

Kate

I am getting a little impatient waiting for AF. Have settled in at my mums and waiting waiting waiting. I should have been cramping or spotting by now, knowing my luck it will come on the weekend when i can't have the BT.
Please send all your AF vibes my way.
xx

Sending AF vibes your way Jaki. What else can bring on AF? Hmmmm maybe some exercise to get the blood flowing etc.

FX that she comes sooner rather than later and preferably before the weekend.

Still waiting.......
Arghhhh driving me nuts!
Can't see it happening before the weekend, maybe next week.

Jaki - FX that AF arrives and she arrives soon. I know what you mean about frustrating. It has to be one of the only times in a girls life that she desperately wants AF.

AFM - So had my BT this morning and another US (2nd US for this cycle). The results are in......... E2 level of 2144 (Tues just gone was 1195) have approx 6 follicles on the go at the moment with the largest being 16mm and the smallest 10mm. Not forgetting the other smaller ones, there was approx 15 in total but only 6 are within ball park for the EPU. Still going with the FSH and Lucrin and have to head back in for an US and BT again Sat morning. Heres hoping that we find out some dates then for EPU cause Im getting anxious now.

Is it ok to get slightly excited now??? Looks like this one will happen for real :)

Get excited hun cause thats awesome!!! :dance: