Hey there, the difference between the two products is that one is a natural and organic product (miessence) where as dermalogica is a professional skin care range.
BAsically, the active ingredients in dermalogica are designed to TREAT more so than miessence, where the ingredients are natural and aim to improve skin by cleaning, cleansing and purifying with organic ingredients.

While you may see quicker results with a professional product, long term use of a natural product if you use it regually should still help clear the skin.

Proactive is really nasty for you skin.