missbec recently mentioned a list of miscarriage exams in one of her posts, I did most of these and they were all fine, except MTHFR. It came back as indicating a genetical mutation ("compound heterozygotous MTHFR mutation"). Apparently this means that I have inherited this condition from one of my parents. It wouldn't be a problem per se if it was only one mutation, but there are 2 of them ("compound") which makes it a risk. I am taking 4mg of folic acid daily (ten times the normal dosis) and will be on heparin once I'm pregnant again. Does anybody have a similar condition and experience to share?
Indy--I'm a little late in your to our little thread! Sorry for the loss you've suffered, I pray that you find comfort and security among the awesome girls we've got here! Big *hugs*
jenushka--Will be thinking of you and your first little angel today! Good luck with your Halloween u/s--can't wait to hear all about your little punkin!
Mel--It can be such a comfort just knowing you're not alone.... we all understand the anguish and angst that come attached with a m/c. Please feel free to vent anytime you need to! We're all here for you! Big *hugs* coming your way!
chappas--Buggers, d@mn AF! Here's some anti vibes for you! Will be here to continue cheering you on with the next cycle!
plc--You have a talent for wording things so beautifully! Always appreciate your posts... they always make me smile! Tomorrow.... chat.... be there, or be square!
Tam--Unfortunately mollycat wasn't blessed in the usual Angel/Jen experience.... had too many distractions going on! But in my own defense, my usual chat time is early in the am... and we chatted in the evening, which is a hectic time for me... so, sorry, mollycat if we were a touch boring last night! Will aim to do better next time! The best chats are the ones that leave your tummy hurting from laughing too much, and you've got tears of laughter in your eyes! So both of you--be there--Friday night!
Easha--Hmmm.... maybe you should get a BT done if today's temp is still above coverline.... could you possibly be UTD during AF? It's possible.... Hope you get some answers! *hugs*
Milla--Sorry to hear about you BT results. I wish I could offer you some advise... hopefully one of the other's will be able to answer your question on the MTHFR. Am I the only one that thinks this looks like an abbreviation for a not-so-nice cuss word? Hope you find the answers you're looking for, Milla! *Hugs* for you!
Angel--Missed you this am! Looking forward to Friday! *kiss*
Krystie--Hope you can join us on Friday! It's been too long! So happy to see you poking your head in, though! It's great to see your beautiful avi again! *kiss* Bellyrubs to little Chyan from her favorite Auntie Hen Jen!
WTH--Thinking of you! *hugs*
Hi's to Toccara, issy, Van, Megsmum, & smi Big for you all!
Me--Just have to add that I had an interesting temp jump today.... hmmmm.... but not looking into anything just yet! Too busy to POAS anyways, but will keep you posted on how things progress! Fingers crossed!
Last edited by jen805; October 16th, 2008 at 11:54 PM.
: added "me"
dellydoo... I think you've made a good decision to go back to work and get out of the house...
Angel Babies...It is simply too hard to leave this special place and all the wonderful support! The benefits are umm...NICE to say the least...let's just say I am pretty stress free at the moment LOL
Thanks ladies for giving me such a warm welcome back to TTC...I appreciate all of you and the support you've given has been 1st class!
Jen, you are very right about the name MTHFR ...I does sound like the 1990 Prince hit:-)
Here are some information I found on the Internet. Maybe it can be useful to some ladies here in the forum. My former ob/gyn didn't want to run the tests; he said they are normally done "after a 3rd m/c". I had to convince him to do the after all, and now I know that there is something I can treat next time. I'm now with a new ob/gyn who is much more proactive and I think that's a good thing. I don't see the point of going through a 3rd m/c with all its pain and heartbreak if I can potentially avoid it by taking a simple blood test.
What's interesting here is that the MTHFR mutation is also linked to anxiety and depression. I have had a major clinical depression 8 years ago for now apparent reason (I was on anti-depressants for 2 years), so I am wondering if there is any link.
I hope the following information will be useful to some of you ladies out there: (as I said, my treatment is high dose folic acid and daily heparin once pregnant)
What is MTHFR?
Methylenetetrahydrofolate reductase (MTHFR) is the name of a gene that produces an enzyme, also called methylenetetrahydrofolate reductase. If a person carries the genetic mutation that inhibits production of this enzyme, it can result in hyperhomocytenemia, which is an elevated level of an enzyme called homocysteine found in blood plasma.
When the body is deficient in methylenetetrahydrofolate reductase, its ability to absorb folate (also known as vitamin B9), such as folic acid, is inhibited. Folic acid and B9 are both essential to the development and health of the fetus.
MTHFR and Pregnancy
Because of a mother with MTHFR?s inability to efficiently metabolize folic acid and vitamin B9, the disorder has been linked to a variety of pregnancy complications such as chromosomal abnormalities, such as Down syndrome, and congenital malformations.
Elevated levels of homocysteine have been associated with placental disease, preeclampsia and recurrent pregnancy loss. 21% of women with high levels of homocysteine experience recurrent pregnancy loss.
Symptoms
Because MTHFR is a blood-based disease with many varieties, symptoms vary depending on the exact mutation of the disease. They can include:
blood clots
depression
anxiety
Detection
Blood testing is the most accurate way to screen for MTHFR. This is especially true if women have a history of complicated pregnancies, including recurrent pregnancy loss and/or stillbirths, or if they have given birth to a child with neural tube defects, such as spina bifida.
Treatment
Taking folic acid can help women with certain mutations of the disease. Folic acid can be found in eggs, dark leafy vegetables, such as spinach and broccoli, oranges and orange juice and legumes, such as peas and dried beans. Vitamin supplements also contain folic acid.
Jen Jen.... i sooooo sowwwwwwyyyyyyyy....... i went out to the movies...well and diner... couldnt help it.... i ve been stuck at home over 2 weeks coming up to3...... I said to DHl... what can we do for dinner.... DS1 came in and i asked him... and he said how bout going out to dinner and then to a movie.... so I thought... what a damn fine idea... bit of quality family time.... PS.. movie was bloody funny... was a silly Australian one with a cameo appearances from a couple of my favourite football players.
Anyway i jumped straight into chat when i got back but i know you would have already been gone for school..... sorry
Milla.... what a word "Methylenetetrahydrofolate" i dont think I ve ever seen a word that long... it looks misspelt... didnt touch it honest.... but thanks for the info.
Smi.... its good to have those BENEFITS occasionally..... I know i used to ENJOY them... to say the least.... I ended up marrying him... but it wasnt the plan at the time ohhh still enjoy them... dont you worry....
FIFI... good to catch up this morning.... hope the next 6 days fly past.... i m sure everything will be fine
Ohhh and I am soooo dobbing on Jen Jen...... now to everyone who has been in Friday night chats.... when you go to leave... Jen Jen will put it on you about piking so early.... mind you its like 12 or 1am........ so here I am off work.... so i figure... lets make this easier and i ll catch up with her nice and early her time..... what does nana do... she chats for a while and pikes... its like 9.30 her time or something like that.... but she has to head off to bed...... LMAO.... what jen jen... did you have the little grandma nighty with matching grandma undies on and a little night time bonet. i can picture you... did you need the walking frame to make it from the computer to the bed ahhh i m loooooooosing it here... i d better stop before i choke.
Esha..... no idea about temps hun.... ask grandma up above... she would know
Molly... good to catch up today... although breif..... looking forward to tomorrow night instead
Tam.... was great getting to know you better the other night..... my throat was soooo sore girl..... DH and Both DS s were laughing at how stupid i sounded
BB good to see you had a nice day yesterday..... my parent s went out also and brought candels.... and lit at 7pm..... then rang me at 8 to proudly announce that they did...... doesnt life get funny sometimes. I really do appreciate that they did it though.
Well thats about me caught up..... Krystie... hopefully you and little chyan can keep it together tomorrow night long enough to pop your head in... looking forward to seeing everyone there..
Take care... huge hugs to everyone including anyone i ve missed.
some medical issues
to our little thread! Sorry for the loss you've suffered, I pray that you find comfort and security among the awesome girls we've got here! Big *hugs*
vibes for you! Will be here to continue cheering you on with the next cycle! 
Always appreciate your posts... they always make me smile! Tomorrow.... chat.... be there, or be square! 
Hope you find the answers you're looking for, Milla! *Hugs* for you!
i m sure everything will be fine
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