I think lack of sleep is making her normal aggression into something out of this world (beeeeeen there, you have my sympathies xoxo). That's why I like swimming because it's a total full body thing and I don't think either of my non sleeping, overstimulated, hypermaniacs could ever fight a good deep sleep after a swim.
Best to make sure to have a big feed close at hand so she is full when she finally knocks out.

It's a crap cycle I hope you can break it.
Geez there are some great ideas and advice in here though! Well done laydeez xoxo