Bub needs to have the Losec around 1/2 an hour before the feed so it has time to start working.

When I dissolved Zander's I just used a tiny amount of water otherwise it was a struggle to get him to take the lot. 1-2ml at the most I used, but it's trial & error to what bub can handle. If he prefers more liquid do that, if he can handle it with less then that's fine also.

I'd check with your Dr as well whether to do it all at once because it may wear off before the night feeds if you do it in the morning IYKWIM. That's why we did half in the morning then half at night so it covered the whole day/night.