I also found the S26 LF didn't fix Chloe's constipation (did help her ezcema though!) My family/community health nurse (or whatever you call them) advised me that s26 fomulas are bad for constipation. She also said steer clear of any of the 'gold' versions of formula as they have high iron contents. Before we changed her to S26 LF she suggested Karicare or Heniz Nurture formulas.