Gonal-F/Puregon & spotting/bleeding

[Lovenhope]

I know this is an old thread but I just did a google search and was directed here in BB. I should have come straight to BB.
I am having the same problem.
I had my period Last week, starting on Monday. I started puregon on Friday (4 injections) & started mild cramping and spotting .
I rang the clinic but because I'm due for a BT tomorrow, they told me to wait til then.
I'm so emotional I don't know what to do with my self. Can anyone tell me what it means? Will my puregon dose be increased? Any ideas?

[Acacia]

Hi Sandy,

I understand how difficult and emotional it can be when you have no idea what your body is doing when you first start IVF treatment. Hang in there, and ask lots of questions if you need to here - the ladies on BB are so supportive and knowledgeable.

It's good that you're going to be able to have a BT tomorrow, even though it was due anyway. Make sure that you make the nurses aware that you are concerned and stressed about it and make sure they are able to offer you an explanation of what they think is going on, and what will be the next step of action if required after the BT. Ask to speak to your FS if you aren't happy with their explanation. You deserve to be reassured and to know what the possibilities are.

So you know, after I wrote this thread back when I had my first IVF cycle, I continued to have proper AF-type bleeding for a couple of days (less amount of time than normal AF though) and then it stopped very quickly and my stim cycle was able to continue normally. The only thing that was different was that I needed to be on the Gonal-F/Puregon for an extra couple of days to counteract the loss and build my lining a little more before EPU.

I think that as your oestrogen levels increase and build up whilst on the Puregon, this will stop any spotting/bleeding you are currently experiencing now. I don't know whether your FS will want to increase the dose, but they may do what my FS did, which was to monitor you again and extra after this BT to see your levels, perhaps do a scan to see your lining (I didn't have any BTs, just scans to see my lining and follicles), and if they can see that your oestrogen levels are rising nicely, despite the spotting and that your lining is building back up if they do a scan, hopefully everything will continue as per normal, perhaps just a little longer on the Puregon before you will be ready for trigger.

Good luck, I hope the BT shows everything is going along well, and if so, you can be pretty sure that the spotting should stop as your lining starts to thicken more and become more stable as time goes on during this cycle.

Try to keep breathing, hang in there even though I know you're scared and confused, and know that there's plenty of hope that everything will work out fine this cycle - my situation in this thread is proof!


Miss C

[Lovenhope]

Thank you so much for your reply MissC. I am definitely feeling a lot better about it. Your words were very reassuring. I got my results back this afternoon. My levels are increasing and the FS said (via the nurse) that as my hormone increases the spotting should stop. I have another BT & U/S on Friday to see how things are going. Thanks again.

[Acacia]

That's great, Sandy! Very glad to hear everything is on track and I'll have everything crossed for you for this cycle. I'm here if you need to ask anything - I remember having so many questions in my first cycle when I wanted to understand and know as much as possible so I was able to keep calm and focussed on getting my BFP.

Good luck - wishing you a big BFP at the end in a few weeks time

[Lovenhope]

Thanks again MissC. Sometimes I find I don't like the answers to my questions, but I still rather know. I have just googles polycystic ovaries and IVF. I came up with poor quality eggs and OHSS. I can't win. I think I better attempt to trust the professionals who are caring for me.
It is so great to see your avatar with bub. Gives me hope that I may get my dream.

[butterfly_warrior]

Sandygirl, try not to let the PCOS, OHSS and poor egg quality thing get you down. I don't have time for a long post at the moment, but I have ridden that rollercoaster and come out the other end. There's stuff you can do to help avoid OHSS if you are particularly prone to it (like me), when I tried it for my third stim cycle, I not only got my first fresh transfer, but I got my precious boy. Let me know if you need more info.

BW

[Lovenhope]

BW, thanks. I would love some extra info when you get a chance. The scan this morning showed lots of follies, more than expected. She told me to start drinking 2L of water a day. I really want to do everything I can to avoid OHSS and not waste a cycle.