BW - thanks for the info. I researched it a bit after your post. It looks like I maybe should up my B6 (was 75mg, but did not want to lengthen my luteal phase, so switched back to just the 50mg that is in my multi). I am enquiring with my FS about heparin/aspirin which seems to help clotting. As my homocystine levels are ok he probably won't think it necessary.

Redlady - the PGD will not help with the double MTHFR gene, however it may rule out a few chromosonal abnormalities. I regret not doing the NK biopsy (which is part of the MC investigation program) because I did a blood test after the last MC and one of my results came back borderline. Problem is, my period was late, so it was not performed at the right time of the cycle, so I do not know if the result would have been worse. My FS is going to try and look into this. Meanwhile, I cannot perform the test as I am have started an IVF cycle and the test cannot be done when you have taken Provera (it affects the results IYKWIM).

Meredith - the SCSA test was very important for my testing, The DNA fragmentation may in some way (and I don't know how it all works) contribute to my chromosonal losses. But DH has been taking BioAce Excel (massive antioxident ****tail) amongst his other vitamins, so it may have helped the results. It was automatically a part of the MC investigation program I did, so Sydney IVF (who run the program) must think it is worth investigating.