Dq Alpha testing

[bub]

Hello Ladies
I am new to this forum although not new to ivf and infertility.

I have had 20 IVF cycles and several miscarriages, Recently I was told I may have NK cells after a uterine biopsy so I recieved all the treatment for that, this included steroids, clexane and several other drugs with no luck.

After trying every protocol available I have recently had a consult with a US doctor who is suggesting my problem is DQ alpha matching. That is my dna and my husbands are so closely matched my body is killing off all the embryos.

Now I am in the process of sending my blood over to the US and having it tested since according to him there are no labs in AUstralia that can confirm this.

I was wondering if anybody has gone done this path or if they are aware of this particular alloimmune disorder.
thanks
Constance2

Hi Constance,
I too have elevated N/K cells and poor implantation with ivf. I also, use Monash Ivf, and it appears they only use prednisone for N/K cell treatment. Because I have a stong autoimmune history, I have N/K cell activation. Initially, I seeked a second opinion with Dr Sacks in Sydney and he found the elevated N/k cells and said he believed it to be the contributer to my miscarriages.
I also, have consulted with Dr Sher, and he his opinion was he didnt think an australian Fertility Specialist would keep me pregnant with australia protocol of not using IVIG therapy. '
I am still childless, and wondering how you have gone with your treatment?
It is so confusing where to turn.
Love to hear from you.
kirsty