Sara69-Thank's hubby and i spoke about pgd last night and he said if we could afford it we would give it a go but i was told today that the genetisist has sent off tissue samples as they suspect PALLISTER HALL SYNDROME or SMITH LEMLI OPITZ SYNDROME or somthing similar and they can't detect those through pgd only in CVS or AMNIO as they need to find an enzym which is not possible in pgd but they first have to isolate the gene anyway i will keep you up to date cross fingers it's pallister hall syndrome as that one doesn't have to be carried by the parent's it can be a one off mutation.