hey zoe
yup you need to have a certain number of posts to be able to PM

Without going into too much personal details as it is a public form
in general
Not every cell in your body has the same DNA make up
men who are mosaic, (have a combo of both XXY and XY cells) have the chance of their arm may be affect by Klinefelters, but their legs may not- that is why it is a syndrome.
There is a chance with mosaic men that they could still produce sperm. Even if its a tiny bit

I know of a melbourne clinic who 10 years ago were having success extracting sperm through a biopsy of klinefelters men and successfully using ISIC to fertalise eggs and get a successful pregnancy.
even if sperm count is really low- they still may be able to get sperm through this technique. After all it only takes one sperm!!! LOL
good luck and let us know how you go!!!!!

Hi again,

Thanks so much for your reply, it's really nice to know there are people who are willing to listen and help you when you are having a really hard time...

It's a really lovely welcome to this forum

We are yet to find out if he is a mosaic Klinefelters, but considering his zero sperm count, very high FSH (42) and LH (19.9) and all of his 'physical attributes' fitting the stereotype, we are already pretty much convinced that he is probably non-mosaic..

I was wondering, did you know if any of the men from the Melbourne trial were non-mosaic? Did they have zero sperm counts or just very low counts?

There is some promising data I have found in a paper here:

http://humrep.oxfordjournals.org/con...3/588.full.pdf

But then again, these are all seemingly 'miracle' cases considering how many men are affected by this condition and how many are able to have successful biological children through reproductive technologies.. It's kinda weird, don't you think.. That so very little publicity is attached to Klinefelter's, especially when it is the most common genetic mutation found in the male population.. ?