Chez, I did suffer from OHSS. It was hell.

I started on 150IU of puregon and didn't respond. I was increased to 300IU, and two doses later I'd responded to the extent where my ovaries hurt like hell when someone (my acupuncturist) pressed on my tummy. From the next blood test my FS was madly cutting my puregon dose back to try to keep things under control... All I can say now is, if you are concerned, don't do what I did and blindly follow instructions. Call the clinic and speak to them and if you need your dose cut back, the sooner that happens, the better.

On the slightly better news side of things - it generally won't cause a cycle to be cancelled as long as you have enough leading follicles (some nice big follies, rather than lots and lots of little ones), but you may not be able to have a transfer, and all embryos may need to be frozen. And that's not all as bad as it sounds - look where we are now! And you get to avoid the crinone!

You're quite safe to take panadol or panadeine if you have pain. By the time I got to EPU I had pain with every single step because my ovaries were so swollen. You should also get started on gatorade or powerade - they help combat dehydration from the fluid that leaks into your abdomen. Probably most important after your trigger and definitely after EPU.

The thing with OHSS is that it gets worse with pregnancy. It improves when AF arrives. That siad, I was still out of action and couldn't fit into my normal clothes for three weeks, even though AF arrived a week after my EPU.

Seriously, I learned the hard way - if you think that's where things are headed, get on the phone to the clinic and don't give up until they've brought you in to be checked out. It's not the end of the world if it does happen, but it's also a pretty unpleasant state to be in, too.

Good luck, Chez.

BW