Every person has 2 chomosome 18s. You get two copies of every chromosome. Having 3 copies of a chromosome or only one copy can cause issues, but this is usually diagnosed via CVS or amnio. There can also be a segment of the chromosome missing or extra. They can do amnio up to just before birth.
She needs to ask for a second opinion, or get a genetic counsellor or social worker (in a smaller hospital) to find out and explain what is happening.
She definately needs a second opinion. I had an amnio at 23wks with Emmanuel, if they picked up T18 at 18wks why on earth didn't they tell her and send her for an amnio then and organize genetic counselling. I really feel for your sister, doesn't sound like she has been looked after medically.
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