I have read the same as Kristin about it being safe in the 2nd and 3rd Trimester. I'm going to speak to my Ob about it today. I work in an Accident and Emergency Dept and I come into contact with sick ppl all the time. I have had the flu vax every year for the past 6 years or so and have never had the flu and get 1 mild to moderate cold per year. But I am pretty hardy, and don't get sick much at the best of times.