From one who never really ended up building her supply up to adequately feed The Monster, all I can tell you is what my LC told me: Express every 3 hours at night and every two to three hours during the day.
More importantly, if you are not yet using a really good double pump, please consider it. The Medela Symphony really made those night-time expresses bearable for me. It is really easy to use and can be rented relatively cheaply from many chemists.
Best of luck with the feeding - I am thinking of you and your lovely family xxx
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